Description
Lonacort Injection contains Triamcinolone Acetonide, a corticosteroid used for its strong anti-inflammatory, anti-allergic, and immunosuppressive properties. It is administered by injection to treat severe allergies, arthritis, joint pain, skin conditions, and other inflammatory disorders that are not adequately controlled with oral medications.
Ingredients
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Active ingredient: Triamcinolone Acetonide 40 mg/ml
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Excipients: Benzyl alcohol, polysorbate, sodium chloride, water for injection (composition may vary by manufacturer).
Drug Class
Dosage Form
Uses / Indications
Lonacort is used in the treatment of:
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Rheumatoid arthritis, osteoarthritis (joint pain, inflammation)
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Severe allergies (seasonal, drug, or contact allergies)
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Dermatologic conditions (eczema, psoriasis, keloids, lichen planus)
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Respiratory disorders (asthma, allergic rhinitis)
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Autoimmune diseases (systemic lupus erythematosus, sarcoidosis)
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Inflammatory bowel disease (ulcerative colitis, Crohn’s disease)
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Hematologic disorders (anemia, thrombocytopenia)
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Certain cancers (as part of palliative treatment)
Dosage (General guidelines – individualized by physician)
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Adults (IM use): 40 mg as a single injection; may repeat at intervals depending on condition.
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Intra-articular / intralesional: 5–40 mg depending on size of joint or lesion.
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Children: Dose adjusted by body weight and medical need.
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Treatment duration should be kept as short as possible.
In Case of Overdose
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Symptoms: Cushing’s syndrome, high blood sugar, electrolyte imbalance, increased infection risk.
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Management: Symptomatic treatment, gradual dose tapering — do not abruptly stop long-term use.
Missed Dose
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Take as soon as remembered if scheduled.
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Do not double dose — wait for next scheduled injection.
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Injections are usually given by a healthcare provider, minimizing missed doses.
How To Use
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Administered only by healthcare professionals.
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Routes: Intramuscular, intra-articular (into joints), or intralesional (into skin lesions).
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Do not self-inject unless directed and trained by a doctor.
When Not to Use (Contraindications)
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Hypersensitivity to Triamcinolone or other corticosteroids.
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Systemic fungal infections.
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Viral infections (herpes, varicella, vaccinia).
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Recent live vaccinations.
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Injection into infected joints, unstable joints, or directly into tendons.
Side Effects
Common:
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Pain or redness at injection site
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Fluid retention, swelling
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Increased appetite, weight gain
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Mood swings, insomnia
Serious:
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Cushingoid features (moon face, fat redistribution)
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Osteoporosis, muscle weakness
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High blood pressure, high blood sugar
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Increased risk of infections
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Eye problems (glaucoma, cataracts)
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Stomach ulcers or bleeding
Precautions & Warnings
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Long-term use may cause adrenal suppression — taper off gradually.
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Monitor blood pressure, blood sugar, and bone health during therapy.
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Use with caution in diabetes, hypertension, peptic ulcer disease, infections, and osteoporosis.
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Avoid exposure to infections like chickenpox or measles.
Drug Interactions
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NSAIDs (e.g., ibuprofen, aspirin): ↑ risk of GI bleeding/ulcers.
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Diuretics: ↑ risk of electrolyte imbalance.
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Antidiabetic drugs: Reduced effectiveness.
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Live vaccines: Contraindicated due to suppressed immune response.
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Cytochrome P450 inducers (e.g., rifampicin, phenytoin): May reduce steroid efficacy.
Storage / Disposal
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Store at below 25°C, protect from light.
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Do not freeze.
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Keep out of reach of children.
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Dispose of unused/expired vials properly — do not flush in wastewater.
Control Drug / Prescription Status
Quick Tips
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Lonacort is a powerful anti-inflammatory injection used when oral therapy is not effective.
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Do not stop treatment suddenly after prolonged use — taper dose as directed.
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Inform doctor if you have diabetes, high blood pressure, or recent infections.
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Report unusual weight gain, persistent infections, or vision changes.
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Regular follow-up and lab monitoring are important during therapy.