Provas Injection (300mg/2ml) – Antifibrinolytic for Bleeding Control | 5 Ampoules

Description

Provas (300mg/2ml) Injection contains Tranexamic Acid, an antifibrinolytic medicine that helps reduce or prevent excessive bleeding. It works by preventing the breakdown of blood clots, making it useful in surgeries, trauma, heavy menstrual bleeding, nosebleeds, dental procedures, and other conditions where bleeding needs to be controlled.

Ingredients

• Active Ingredient: Tranexamic Acid (300mg/2ml)

• Inactive Ingredients: Sterile water, excipients for injection stability

Drug Class

• Antifibrinolytic Agent

Dosage Form

• Injection (Intravenous or Intramuscular, 2ml ampoule)

• Pack: 5 Ampoules

Uses

• To prevent or reduce bleeding during and after surgery

• Control of heavy menstrual bleeding (menorrhagia)

• Management of nosebleeds (epistaxis)

• Dental procedures in patients with bleeding disorders

• Trauma-related bleeding (internal and external)

• Postpartum hemorrhage (bleeding after childbirth)

• Patients with hemophilia during dental extraction or minor surgery

Dosage

• Adults:

  • Surgical bleeding: 10–15 mg/kg IV before surgery, then repeated every 6–8 hours

  • Heavy menstrual bleeding: As prescribed by doctor

• Children: Dose adjusted by weight and condition
  ⚠️ Must be given by a healthcare professional only.

In Case of Overdose

• Symptoms: Nausea, vomiting, dizziness, low blood pressure, seizures

• Immediate medical attention required

Missed Dose

• If missed, take as soon as remembered

• Skip if near next scheduled dose

• Do not double dose

How To Use

• Administered via intravenous (IV) or intramuscular (IM) injection by a healthcare professional

• Should not be self-administered without supervision

When Not to Use

• Allergy to Tranexamic Acid

• History of blood clots (DVT, pulmonary embolism, stroke)

• Active intravascular clotting conditions

• Severe kidney disease (without dose adjustment)

• Subarachnoid hemorrhage (bleeding in brain)

Side Effects

• Common: Nausea, vomiting, diarrhea, headache, dizziness

• Less common: Low blood pressure, muscle pain, fatigue, visual disturbances

• Rare but serious: Seizures, blood clots (DVT, PE, stroke)

Precautions & Warnings

• Use with caution in patients with kidney disease (dose adjustment needed)

• Monitor for signs of blood clots

• Should not be used long-term without medical supervision

• Avoid driving if experiencing dizziness or vision problems

• Use in pregnancy and breastfeeding only if prescribed by a doctor

Drug Interactions

• Oral contraceptives → ↑ risk of blood clots

• Factor IX complex concentrates → ↑ risk of thrombosis

• Anticoagulants (warfarin, heparin) → reduced effectiveness of therapy

• Other pro-coagulant medicines → ↑ clotting risk

Storage/Disposal

• Store below 25°C, away from direct sunlight

• Keep ampoules in original packaging

• Dispose of safely as per medical waste guidelines

Control Drug

• Not a controlled substance

• Prescription required

Quick Tips

• Inform your doctor about any history of blood clots before starting this injection

• Stay hydrated and avoid prolonged immobility (to reduce clot risk)

• Report any sudden chest pain, leg swelling, or difficulty breathing immediately

• Do not stop or start this medicine without medical advice