Macrobac (250mg) 6 Tablets – Clarithromycin Antibiotic for Bacterial Infections

Description:

Macrobac (250mg) Tablets contain Clarithromycin, a broad-spectrum macrolide antibiotic used to treat a variety of bacterial infections. It works by stopping bacteria from producing essential proteins required for their growth and survival.
This medicine is commonly prescribed for respiratory tract infections, ear, nose, and throat infections, skin and soft tissue infections, and stomach ulcers caused by Helicobacter pylori (H. pylori).

Ingredients:

• Active Ingredient: Clarithromycin 250mg

• Inactive Ingredients: Microcrystalline cellulose, lactose monohydrate, magnesium stearate, croscarmellose sodium, and coating materials.

Drug Class:

• Macrolide Antibiotic

Dosage Form:

• Film-Coated Tablet

Uses:

• Treatment of respiratory tract infections (pneumonia, bronchitis)

• Ear, nose, and throat infections (sinusitis, pharyngitis, tonsillitis)

• Skin and soft tissue infections

• Stomach and duodenal ulcers due to H. pylori (with other medicines)

• Mycobacterial infections (especially in immunocompromised patients)

Dosage:

• Adults: Usually 250mg twice daily for 7–14 days (as prescribed).

• Children: Dose adjusted according to weight.

• May be taken with or without food, but taking it after meals reduces stomach upset.

• Follow your doctor’s instructions strictly for dosage and duration.

In Case of Overdose:

Symptoms: Nausea, vomiting, abdominal pain, confusion, and headache.
➡️ Seek immediate medical attention or go to the nearest hospital emergency department.

Missed Dose:

• Take the missed dose as soon as you remember.

• Skip it if it’s almost time for the next dose.

• Do not double the dose to make up for a missed one.

How To Use:

• Swallow the tablet whole with a glass of water.

• Do not crush or chew the tablet.

• Take doses at evenly spaced intervals.

• Complete the full prescribed course even if symptoms improve early to avoid antibiotic resistance.

When Not to Use:

• Known allergy to Clarithromycin, Erythromycin, or other macrolides.

• Liver dysfunction or cholestatic jaundice history due to Clarithromycin use.

• Concomitant use with cisapride, pimozide, or ergot derivatives.

• Caution in pregnant or breastfeeding women (consult your doctor).

Side Effects:

Common:

• Nausea, vomiting, diarrhea

• Abdominal pain

• Headache

• Change in taste (metallic taste)

Serious (seek medical help):

• Severe allergic reactions (rash, itching, swelling)

• Jaundice (yellowing of skin or eyes)

• Irregular heartbeat

• Persistent or bloody diarrhea (may indicate C. difficile infection)

Precautions & Warnings:

• Inform your doctor about liver, kidney, or heart conditions before using.

• Avoid alcohol during treatment.

• May interact with several medications — always share your full medication list.

• Prolonged use may result in secondary infections such as fungal overgrowth.

• Use with caution in elderly patients.

Drug Interactions:

• Warfarin – may increase bleeding risk.

• Statins (Simvastatin, Lovastatin) – risk of muscle toxicity.

• Carbamazepine, Theophylline, Phenytoin – altered drug levels.

• Rifampicin, Efavirenz – may reduce Clarithromycin effectiveness.

• Digoxin, Verapamil – may increase cardiac risks.

Storage/Disposal:

• Store below 25°C, away from heat and moisture.

• Keep in original packaging until use.

• Keep out of reach of children.

• Do not use after expiry date.

• Dispose of unused tablets responsibly; do not flush down the toilet.

Control Drug:

• Prescription-Only Medicine

Quick Tips:

• Take the medicine at the same time daily for consistent blood levels.

• Do not stop early, even if you feel better.

• Report persistent diarrhea, rash, or yellowing of skin to your doctor immediately.

• Avoid grapefruit juice as it may affect drug absorption.

• Maintain good hydration throughout the course.