Description
Natrilam (1.5/5mg) Tablets combine Indapamide (a thiazide-like diuretic) and Amlodipine (a calcium channel blocker). This unique dual-action formula helps to lower high blood pressure (hypertension) effectively by relaxing blood vessels and removing excess salt and water from the body.
Regular use of Natrilam helps reduce the risk of heart attack, stroke, and kidney damage by maintaining healthy blood pressure levels. It is often prescribed for patients who require combination therapy for better blood pressure control.
Ingredients
Drug Class
Dosage Form
Uses
Natrilam is used for:
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Treatment of essential hypertension (high blood pressure)
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Prevention of cardiovascular complications (heart attack, stroke, kidney disease)
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Management of patients not adequately controlled on Amlodipine or Indapamide alone
Dosage
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Adults: One tablet once daily, preferably in the morning.
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Take regularly at the same time each day.
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Dosage may be adjusted by your doctor based on blood pressure response.
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Do not exceed prescribed dose or stop medication without consulting your doctor.
In Case of Overdose
Symptoms may include:
Action: Seek immediate medical attention or go to the nearest emergency department.
Missed Dose
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Take the missed dose as soon as you remember.
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If it’s almost time for your next dose, skip the missed one.
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Do not double up to make up for a missed tablet.
How To Use
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Take Natrilam orally with a glass of water, once daily.
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It may be taken with or without food, preferably in the morning.
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Continue taking even if you feel well — hypertension often has no symptoms.
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Follow a low-salt diet and maintain a healthy lifestyle for best results.
When Not to Use
Do not use Natrilam if you:
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Are allergic to Amlodipine, Indapamide, or other sulfonamides.
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Have severe liver or kidney impairment.
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Have low potassium or sodium levels.
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Have low blood pressure (hypotension).
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Have heart failure or aortic stenosis.
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Are pregnant or breastfeeding, unless advised by your doctor.
Side Effects
Common side effects:
Serious (rare) side effects:
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Irregular heartbeat
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Shortness of breath
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Severe allergic reactions (rash, itching, swelling)
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Severe drop in blood pressure
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Electrolyte imbalance (low potassium or sodium)
If any serious side effects occur, stop medication and seek medical help immediately.
Precautions & Warnings
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Monitor blood pressure and kidney function regularly.
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Use cautiously in patients with heart, kidney, or liver problems.
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Avoid alcohol and grapefruit juice, which can intensify side effects.
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Stay hydrated and avoid overheating, as diuretics can cause dehydration.
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Inform your doctor if you experience muscle weakness, cramps, or irregular heartbeat — may indicate electrolyte imbalance.
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May cause dizziness — avoid driving or operating machinery until you know how it affects you.
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Not recommended during pregnancy or breastfeeding unless clearly needed.
Drug Interactions
Tell your doctor if you are taking:
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Other blood pressure medicines (ACE inhibitors, ARBs, beta-blockers)
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Diuretics or potassium supplements
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NSAIDs (e.g., ibuprofen, diclofenac) — may reduce BP-lowering effect
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Lithium — increased toxicity risk
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Antiarrhythmics or heart medicines (digoxin)
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Antifungal or antibiotic drugs (erythromycin, clarithromycin)
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Antidepressants or antipsychotics
Storage/Disposal
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Store below 30°C, in a cool, dry place away from light and moisture.
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Keep out of reach of children.
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Do not use after the expiry date.
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Dispose of unused tablets properly — do not flush or throw in household waste.
Control Drug
Quick Tips
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Take Natrilam in the morning to reduce nighttime urination.
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Continue taking even if you feel fine — stopping suddenly may raise BP.
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Avoid excessive salt intake.
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Stay well hydrated, especially during hot weather.
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Regularly monitor blood pressure and kidney function.
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Rise slowly from sitting or lying positions to prevent dizziness.
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Follow your doctor’s dietary and exercise recommendations.