Description
Natrilix (2.5mg) Tablets contain Indapamide, a thiazide-like diuretic used to manage high blood pressure (hypertension) and fluid retention (edema). It works by helping the kidneys remove excess salt and water from the body while relaxing blood vessels, which lowers blood pressure and improves circulation.
Regular use of Natrilix helps prevent heart attack, stroke, and kidney complications related to hypertension. It is well-tolerated and suitable for long-term therapy under medical supervision.
Ingredients
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Active Ingredient: Indapamide 2.5 mg
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Inactive Ingredients: Lactose monohydrate, cellulose, povidone, magnesium stearate, and other standard excipients
Drug Class
Dosage Form
Uses
Natrilix is prescribed for:
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Treatment of essential hypertension (high blood pressure)
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Reduction of edema (fluid retention) caused by heart, kidney, or liver conditions
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Prevention of cardiovascular events (heart attack, stroke, and heart failure)
Dosage
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Adults: One tablet (2.5 mg) once daily, preferably in the morning.
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Can be taken with or without food.
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Do not exceed the prescribed dose.
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Your doctor may adjust the dose depending on your blood pressure and response to therapy.
In Case of Overdose
Symptoms:
Action:
Seek immediate medical attention or go to the nearest hospital emergency department.
Missed Dose
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Take the missed dose as soon as you remember.
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If it’s close to your next dose, skip the missed one — do not double up.
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Continue your regular dosing schedule.
How To Use
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Take the tablet once daily in the morning with a full glass of water.
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Can be taken with or without food.
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Avoid taking it late in the day to prevent nighttime urination.
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Continue taking even if you feel fine — hypertension usually has no symptoms.
When Not to Use
Do not use Natrilix if you:
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Are allergic to Indapamide or other sulfonamides.
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Have severe liver or kidney disease.
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Have low potassium or sodium levels in the blood.
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Have gout or high uric acid levels.
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Are pregnant or breastfeeding, unless prescribed by a doctor.
Side Effects
Common side effects:
Rare but serious side effects:
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Severe drop in blood pressure
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Irregular heartbeat
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Electrolyte imbalance (low potassium, sodium, or magnesium)
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Allergic skin reactions (rash, itching, swelling)
If you experience any severe or persistent side effects, stop use and seek medical attention.
Precautions & Warnings
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Monitor blood pressure, electrolytes, and kidney function regularly.
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Use with caution in patients with diabetes, gout, or heart disease.
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Avoid alcohol, as it can increase dizziness.
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Stay hydrated; dehydration may worsen side effects.
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Inform your doctor if you are on other diuretics or heart medications.
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Avoid overheating during exercise or hot weather.
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Not recommended for pregnant or breastfeeding women unless absolutely necessary.
Drug Interactions
Tell your doctor about all medicines you take, especially:
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Other blood pressure medicines (ACE inhibitors, ARBs, beta-blockers)
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Diuretics (furosemide, hydrochlorothiazide)
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NSAIDs (ibuprofen, diclofenac) – may reduce Natrilix effectiveness
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Lithium – risk of toxicity increases
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Digoxin – may increase risk of low potassium
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Corticosteroids – may worsen electrolyte imbalance
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Antiarrhythmic or antipsychotic drugs
Storage/Disposal
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Store below 30°C, away from direct light and moisture.
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Keep out of reach of children.
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Do not use after the expiry date.
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Dispose of unused tablets properly; do not flush into drains or toilets.
Control Drug
Quick Tips
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Take your dose in the morning to avoid sleep disturbance from urination.
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Do not stop taking Natrilix abruptly — your BP may rise suddenly.
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Limit salt intake and follow a balanced diet.
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Stay hydrated, especially in hot weather.
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Regularly monitor blood pressure and electrolyte levels.
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Avoid alcohol and excessive caffeine.
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If you feel dizzy, rise slowly from sitting or lying positions.
