Description
Natrilix SR (1.5mg) contains Indapamide (Sustained Release), a thiazide-like diuretic used primarily to treat high blood pressure (hypertension) and fluid retention (edema). The “SR” (Sustained Release) formulation ensures a gradual release of medicine throughout the day, offering consistent blood pressure control with a lower risk of electrolyte imbalance.
By helping the kidneys eliminate excess water and salt while relaxing blood vessels, Natrilix SR effectively lowers blood pressure, improving heart, brain, and kidney health and reducing the risk of heart attack or stroke.
Ingredients
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Active Ingredient: Indapamide 1.5 mg (Sustained Release)
 
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Inactive Ingredients: Lactose monohydrate, povidone, magnesium stearate, cellulose, hypromellose, and other pharmaceutical excipients.
 
Drug Class
Dosage Form
Uses
Natrilix SR is used for:
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Essential hypertension (high blood pressure)
 
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Prevention of heart attack, stroke, and kidney disease in hypertensive patients
 
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Reduction of edema associated with heart or kidney conditions
 
Dosage
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Recommended Dose: One tablet (1.5 mg) once daily, preferably in the morning.
 
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Can be taken with or without food.
 
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Follow your doctor’s directions carefully.
 
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Do not exceed the prescribed dose.
 
In Case of Overdose
Symptoms may include:
Action:
Contact your doctor or visit the nearest hospital immediately if overdose is suspected.
Missed Dose
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Take the missed dose as soon as possible.
 
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If it’s near the time for the next dose, skip the missed one.
 
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Do not double dose to make up for a missed tablet.
 
How To Use
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Swallow the tablet whole with water — do not crush or chew.
 
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Take it once daily in the morning to avoid nighttime urination.
 
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Continue taking it even if you feel well, as hypertension often has no symptoms.
 
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Combine with lifestyle changes like a low-salt diet, regular exercise, and stress reduction for best results.
 
When Not to Use
Do not use Natrilix SR if you:
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Are allergic to Indapamide or other sulfonamides.
 
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Have severe liver or kidney disease.
 
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Have very low potassium, sodium, or other electrolyte levels.
 
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Have gout or elevated uric acid levels.
 
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Are pregnant or breastfeeding, unless specifically advised by your doctor.
 
Side Effects
Common side effects:
Serious but rare side effects:
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Low blood pressure (fainting)
 
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Electrolyte imbalance (low potassium/sodium)
 
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Irregular heartbeat
 
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Allergic skin rash or swelling
 
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Signs of dehydration
 
If you experience serious side effects, stop taking the medicine and seek medical help immediately.
Precautions & Warnings
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Monitor blood pressure, electrolytes, and kidney function regularly.
 
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Use cautiously if you have diabetes, gout, heart disease, or liver disorders.
 
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Avoid alcohol, as it can intensify dizziness or low blood pressure.
 
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Stay hydrated but avoid excessive water intake unless advised.
 
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Inform your doctor if you are taking diuretics, lithium, or antiarrhythmic medicines.
 
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Avoid driving or operating machinery if you feel dizzy or faint.
 
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Not recommended during pregnancy or breastfeeding without medical supervision.
 
Drug Interactions
Tell your healthcare provider about all medications you are using, especially:
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Other antihypertensive drugs (ACE inhibitors, ARBs, beta-blockers)
 
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NSAIDs (ibuprofen, diclofenac) – may reduce effect of Natrilix
 
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Lithium – risk of lithium toxicity
 
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Corticosteroids – may worsen electrolyte imbalance
 
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Antiarrhythmic drugs – may increase risk of irregular heartbeat
 
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Diuretics or digoxin – may alter potassium levels
 
Storage/Disposal
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Store below 30°C, away from moisture, heat, and sunlight.
 
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Keep out of reach of children and pets.
 
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Do not use after the expiry date printed on the pack.
 
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Dispose of unused or expired medicine properly; do not flush into the toilet.
 
Control Drug
Quick Tips
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Take in the morning to reduce nighttime urination.
 
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Do not stop taking suddenly without consulting your doctor.
 
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Avoid high-salt foods and alcohol.
 
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Stay hydrated, especially during hot weather.
 
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Regularly check blood pressure and electrolytes.
 
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If you feel dizzy, rise slowly from sitting or lying positions.
 
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Combine with a healthy diet and regular exercise for maximum benefit.