X-Plended EZ (20/10mg) Tablets
X-Plended EZ 20/10mg combines Olmesartan Medoxomil (20mg) and Amlodipine Besylate (10mg) to effectively lower high blood pressure. This dual-action formulation relaxes blood vessels, improves blood flow, and reduces heart strain, helping prevent heart attacks, strokes, and kidney complications related to hypertension.
Ingredients
Active Ingredients:
- Olmesartan Medoxomil 20mg
- Amlodipine Besylate equivalent to Amlodipine 10mg
Inactive Ingredients: Microcrystalline cellulose, magnesium stearate, lactose monohydrate, other pharmaceutical excipients
Drug Class
Class: Angiotensin II Receptor Blocker (ARB) + Calcium Channel Blocker (CCB) combination
Category: Antihypertensive
Dosage Form
Form: Film-coated tablet
Pack Size: 10 tablets per pack
Uses
- High blood pressure (Hypertension)
- Patients not controlled on monotherapy with amlodipine or olmesartan
- Reducing the risk of stroke, heart attack, or heart failure
- Protection against kidney damage in hypertensive patients
Dosage
- Adults: One tablet once daily at the same time each day
- Route: Oral; swallow whole with water
- Elderly/renal impairment: Dose adjustment may be required
- 💊 Follow your doctor’s instructions; do not self-adjust dose
In Case of Overdose
Symptoms: Severe dizziness, fainting, significant drop in blood pressure
Action: Seek immediate medical attention or visit the nearest emergency department.
Missed Dose
- Take as soon as you remember
- If near next dose, skip the missed one
- Do not double the dose
How To Use
- Take once daily, with or without food
- Swallow whole with a glass of water
- Take at the same time each day for consistent blood pressure control
- Continue even if you feel well; do not stop suddenly
When Not to Use
- Allergy to amlodipine, olmesartan, or any ingredients
- Pregnancy or planning pregnancy
- Severe liver or kidney impairment
- Severe hypotension
- Cardiogenic shock or aortic stenosis
Side Effects
Common: Dizziness, swelling of ankles/feet, fatigue, flushing, nausea, mild stomach pain
Serious: Severe hypotension, irregular heartbeat, high potassium signs, kidney problems, allergic reactions
⚠️ Seek immediate medical attention for severe dizziness, fainting, or breathing difficulty.
Precautions & Warnings
- Use cautiously in heart failure, liver or kidney impairment
- Avoid excessive alcohol consumption
- Do not take potassium supplements or salt substitutes without consulting your doctor
- Avoid driving if feeling dizzy
- Monitor blood pressure regularly
- Not recommended during pregnancy or breastfeeding
Drug Interactions
- Other antihypertensive drugs (additive BP-lowering effects)
- NSAIDs (may reduce effect of olmesartan)
- Potassium supplements/diuretics (risk of high potassium)
- Lithium (risk of toxicity)
- CYP3A4 inhibitors (may increase amlodipine levels)
- Alcohol (may cause excessive hypotension)
Storage/Disposal
- Store below 30°C, in a cool, dry place away from sunlight and moisture
- Keep out of reach of children
- Do not use after expiry date
- Dispose of unused tablets responsibly according to local regulations
Control Drug
Prescription-only medicine (Not a controlled drug)
Quick Tips
- Take at the same time daily
- Continue even if you feel well
- Avoid high-sodium foods; maintain a balanced diet
- Rise slowly to avoid dizziness
- Stay hydrated, especially in hot weather
- Do not stop abruptly; consult your doctor
- Combine with lifestyle changes: regular exercise, weight management, reduced salt intake
