Description
X-Plended EZ (20/10mg) Tablets combine two powerful antihypertensive medicines — Olmesartan Medoxomil (20mg) and Amlodipine Besylate (10mg). This dual-action formulation helps effectively lower high blood pressure by relaxing blood vessels, improving blood flow, and reducing strain on the heart.
Regular use of X-Plended EZ helps prevent heart attacks, strokes, and kidney complications related to hypertension.
Ingredients
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Active Ingredients:
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Olmesartan Medoxomil 20mg
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Amlodipine Besylate equivalent to Amlodipine 10mg
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Inactive Ingredients: Microcrystalline cellulose, magnesium stearate, lactose monohydrate, and other pharmaceutical excipients.
Drug Class
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Class: Angiotensin II Receptor Blocker (ARB) + Calcium Channel Blocker (CCB) combination
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Category: Antihypertensive
Dosage Form
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Form: Film-coated tablet
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Packaging: 10 tablets per pack
Uses
X-Plended EZ 20/10mg is indicated for:
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High blood pressure (Hypertension)
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Patients not controlled on monotherapy with either amlodipine or olmesartan alone
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Reducing the risk of cardiovascular events such as stroke, heart attack, or heart failure
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Protection against kidney damage in hypertensive patients
Dosage
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Adults: One tablet once daily, preferably at the same time each day.
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Route: Oral; swallow whole with water.
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Elderly or renal-impaired patients: Dose adjustment may be required.
⚠️ Always follow your doctor’s prescribed dose and duration. Do not self-adjust the medication.
In Case of Overdose
Symptoms may include severe dizziness, fainting, or a significant drop in blood pressure (hypotension).
➡️ Action: Seek immediate medical attention or visit the nearest emergency department.
Missed Dose
If you miss a dose, take it as soon as you remember.
If it’s near the time for your next dose, skip the missed dose.
⚠️ Do not double the dose to make up for the missed one.
How To Use
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Take one tablet daily, with or without food.
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Swallow the tablet whole with a glass of water.
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Take at the same time each day to maintain consistent blood pressure control.
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Continue taking even if you feel well; stopping suddenly may cause your blood pressure to rise again.
When Not to Use
Do not use X-Plended EZ if you:
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Are allergic to Amlodipine, Olmesartan, or any of the ingredients.
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Are pregnant or planning to become pregnant (may harm the unborn baby).
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Have severe liver or kidney impairment.
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Suffer from severe hypotension (low blood pressure).
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Have cardiogenic shock or aortic stenosis (heart valve narrowing).
Side Effects
Common side effects:
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Dizziness or lightheadedness
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Swelling of ankles/feet (edema)
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Fatigue or drowsiness
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Flushing (feeling of warmth)
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Nausea or mild stomach pain
Less common but serious side effects:
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Severe drop in blood pressure
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Irregular heartbeat or palpitations
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Signs of high potassium (muscle weakness, slow heartbeat)
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Kidney problems (changes in urine output)
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Allergic reactions (rash, swelling, shortness of breath)
⚠️ Seek immediate medical attention if you experience severe dizziness, fainting, or difficulty breathing.
Precautions & Warnings
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Use with caution in patients with heart failure, liver disease, or kidney impairment.
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Avoid excessive alcohol consumption as it may enhance dizziness or low blood pressure.
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Do not take potassium supplements or salt substitutes without consulting your doctor.
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Avoid driving or operating machinery if you feel dizzy.
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Regular blood pressure monitoring is recommended.
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Not recommended for use during pregnancy or breastfeeding.
Drug Interactions
X-Plended EZ may interact with:
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Other antihypertensive drugs (additive BP-lowering effects)
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NSAIDs (e.g., ibuprofen, naproxen — may reduce the effect of olmesartan)
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Potassium supplements / diuretics (risk of high potassium)
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Lithium (risk of toxicity)
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CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin — may increase amlodipine levels)
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Alcohol (may cause excessive hypotension)
Always inform your healthcare provider about all medications or supplements you use.
Storage/Disposal
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Store below 30°C, in a cool and dry place away from moisture and sunlight.
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Keep out of reach of children.
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Do not use after expiry date.
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Dispose of expired or unused tablets responsibly according to local regulations.
Control Drug
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Not a controlled drug (Prescription-only medicine)
Quick Tips
💡 Quick Tips for Safe Use:
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Take your medicine at the same time every day.
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Continue using even if you feel fine — it helps prevent heart and kidney damage.
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Avoid high-sodium foods and maintain a balanced diet.
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Rise slowly from sitting or lying positions to avoid dizziness.
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Stay hydrated, especially in hot weather.
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Do not stop taking abruptly without consulting your doctor.
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Combine with lifestyle changes like regular exercise, weight management, and reduced salt intake for best results.



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