Description
Zepres 5mg Tablets contain Amlodipine, a long-acting calcium channel blocker (CCB) that relaxes and widens blood vessels, allowing easier blood flow and reducing the workload on the heart.
It is used to treat high blood pressure (hypertension) and chest pain (angina pectoris), and it helps prevent complications such as heart attack, stroke, and kidney damage.
Zepres ensures smooth blood circulation, improved heart performance, and better blood pressure control with once-daily dosing.
Ingredients
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Active Ingredient: Amlodipine Besylate equivalent to Amlodipine 5mg
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Inactive Ingredients: Microcrystalline cellulose, magnesium stearate, sodium starch glycolate, and film coating materials.
Drug Class
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Class: Calcium Channel Blocker (CCB)
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Category: Antihypertensive / Antianginal
Dosage Form
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Form: Film-coated tablet
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Packaging: 20 tablets per pack
Uses
Zepres 5mg is used for:
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High blood pressure (Hypertension)
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Chest pain due to reduced blood supply to the heart (Angina)
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Prevention of heart attack and stroke
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Management of coronary artery disease (CAD)
Dosage
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Adults:
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Usually 5mg once daily.
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Maximum dose: 10mg once daily.
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Elderly or hepatic impairment: Start with 2.5mg daily if required.
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Route: Oral (swallow whole with water, with or without food).
⚠️ Always take the dose prescribed by your physician. Do not adjust or skip without medical advice.
In Case of Overdose
Symptoms may include excessive dizziness, low blood pressure, fainting, rapid heartbeat, or fatigue.
➡️ Action: Seek immediate medical attention or go to the nearest emergency department.
Missed Dose
If you miss a dose, take it as soon as possible.
If it’s near your next dose, skip the missed one and continue your schedule.
⚠️ Do not double the dose to make up for a missed tablet.
How To Use
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Take once daily, preferably at the same time every day.
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Can be taken with or without meals.
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Swallow with a glass of water; do not chew or crush.
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Continue taking it even if you feel well — hypertension often has no symptoms.
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Do not stop taking Zepres suddenly without your doctor’s approval.
When Not to Use
Do not use Zepres if you:
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Are allergic to Amlodipine or any other calcium channel blocker.
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Have severe low blood pressure (hypotension).
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Suffer from cardiogenic shock or severe aortic stenosis.
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Have heart failure or unstable angina unless recommended by a doctor.
Side Effects
Common side effects:
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Swelling of ankles or feet (edema)
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Dizziness, flushing
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Headache or tiredness
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Palpitations
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Nausea or abdominal discomfort
Serious side effects (seek medical help):
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Chest pain or irregular heartbeat
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Fainting or severe dizziness
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Allergic reaction (rash, itching, swelling)
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Shortness of breath or difficulty breathing
Precautions & Warnings
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Use with caution in patients with liver disease, heart failure, or severe hypotension.
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Avoid alcohol — it can enhance blood-pressure-lowering effects.
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May cause dizziness; avoid driving or operating machinery until you know your reaction.
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Inform your doctor if you are pregnant, breastfeeding, or planning pregnancy.
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Monitor blood pressure regularly during use.
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Do not stop medication abruptly without medical advice.
Drug Interactions
Zepres may interact with:
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Other antihypertensives (e.g., beta-blockers, ACE inhibitors) – may increase effect.
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CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, diltiazem) – may increase Amlodipine levels.
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CYP3A4 inducers (e.g., rifampicin, carbamazepine) – may reduce its effect.
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Simvastatin – dose adjustment may be required.
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Grapefruit juice – may enhance Amlodipine levels, use with caution.
Storage/Disposal
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Store below 30°C, in a cool and dry place.
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Protect from moisture and direct sunlight.
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Keep out of reach of children.
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Dispose of expired or unused tablets safely — do not flush or discard in household waste.
Control Drug
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Not a controlled drug (Prescription-only medicine).
Quick Tips
💡 Quick Tips for Safe Use:
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Take your tablet at the same time daily for best results.
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Continue using even if you feel fine — hypertension is often symptomless.
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Get up slowly from sitting or lying positions to prevent dizziness.
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Reduce salt intake and follow a heart-healthy diet.
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Regularly monitor your blood pressure and heart rate.
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Avoid grapefruit juice while taking Zepres.
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Consult your doctor before stopping the medicine.



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