Dermovate-NN 20g Ointment

Dermovate-NN Ointment is a combination topical medication containing clobetasol propionate and neomycin sulfate. It is used to treat inflammatory skin conditions that may also have bacterial infections. The corticosteroid (clobetasol) helps reduce redness, itching, and swelling, while the antibiotic (neomycin) prevents or treats secondary bacterial infections. It is suitable for use on thick, dry, or scaly lesions.

Ingredients

• Active Ingredients:

  • Clobetasol Propionate 0.05%

  • Neomycin Sulfate 0.5%

• Inactive Ingredients:
  White soft paraffin, liquid paraffin, sorbitan sesquioleate, and propylene glycol.

Drug Class
Topical Corticosteroid + Antibiotic Combination

Dosage Form
Ointment (for external use only)

Uses

• Eczema with secondary bacterial infection

• Psoriasis (localized and infected lesions)

• Dermatitis (atopic, contact, or seborrheic) with infection

• Lichen planus and lichen simplex chronicus

• Other steroid-responsive skin conditions complicated by infection

Dosage
Apply a thin layer to the affected area once or twice daily, as prescribed by a healthcare provider. Do not use for more than 7–14 days unless directed by a doctor. Avoid prolonged continuous use to minimize risk of side effects or bacterial resistance.

In Case of Overdose
Topical overdose is uncommon but may lead to systemic absorption, causing adrenal suppression or signs of corticosteroid toxicity. Excessive or prolonged use can also increase the risk of antibiotic-related side effects such as hearing loss or kidney issues. Seek medical attention if unusual symptoms occur.

Missed Dose
Apply the missed dose as soon as possible. If it is almost time for your next scheduled application, skip the missed one. Do not double the dose.

How To Use

1. Clean and dry the affected skin before application.

2. Apply a small amount and gently rub in a thin layer.

3. Do not cover with airtight dressings unless instructed by your doctor.

4. Wash hands after applying (unless the treatment is for the hands).

5. Avoid contact with eyes, mouth, or mucous membranes.

When Not to Use

• If allergic to clobetasol, neomycin, or any component of the ointment

• On untreated viral, fungal, or tubercular skin infections

• On acne, rosacea, or perioral dermatitis

• On the face, groin, or underarms unless specifically prescribed

• In children under 12 years without medical advice

Side Effects

• Burning, itching, dryness, or irritation at application site

• Skin thinning, stretch marks, or discoloration with long-term use

• Increased hair growth (local hypertrichosis)

• Allergic reactions such as rash or swelling

• Systemic effects (rare): adrenal suppression, Cushing’s syndrome

• Prolonged use may cause bacterial resistance due to neomycin

Precautions & Warnings

• For external use only.

• Avoid prolonged use or application to large body areas.

• Use only for infected skin conditions as directed.

• Avoid contact with eyes, mouth, or open wounds.

• Do not use if infection persists or worsens—consult a doctor.

• Inform your healthcare provider if pregnant, breastfeeding, or using other topical medications.

• Long-term use may cause skin atrophy or antibiotic resistance.

Drug Interactions

• Using other corticosteroid-containing or aminoglycoside-containing products (oral or topical) may increase the risk of systemic side effects.

• Avoid concurrent use with other ototoxic or nephrotoxic drugs.

• Always inform your doctor about any medications you are using.

Storage/Disposal
Store below 30°C, away from direct heat and sunlight. Do not freeze. Keep tightly closed and out of reach of children. Dispose of unused or expired ointment according to local pharmaceutical waste guidelines.

Control Drug
Not a controlled drug.

Quick Tips

• Use only on infected, inflamed skin as prescribed.

• Avoid using on broken skin unless advised.

• Do not use for longer than recommended.

• Stop use and consult a doctor if irritation or infection worsens.

• Wash hands after each application.

• Do not share with others to prevent spread of infection.