Zoldap (400mg) 10 Tablets

Zoldap 400mg Tablet contains Duloxetine, a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to manage depression, anxiety disorders, and certain types of nerve pain. It works by balancing serotonin and norepinephrine levels in the brain, improving mood and reducing pain signals.

Ingredients

• Active Ingredient: Duloxetine 400mg

• Inactive Ingredients: Microcrystalline cellulose, magnesium stearate, povidone, starch, and other excipients.

Drug Class

• Antidepressant / SNRI (Serotonin-Norepinephrine Reuptake Inhibitor)

Dosage Form

• Oral Tablet

Uses
Zoldap 400mg is prescribed for:

• Major depressive disorder (MDD)

• Generalized anxiety disorder (GAD)

• Neuropathic pain associated with diabetic peripheral neuropathy

• Fibromyalgia

• Chronic musculoskeletal pain (optional use as prescribed)

Dosage

• Adults: Typically 30–60mg once or twice daily, as prescribed by a doctor.

• Swallow the tablet whole with water.

• Dose may be adjusted based on response and tolerability.

In Case of Overdose

• Symptoms may include severe dizziness, fainting, rapid heartbeat, or seizures.

• Seek immediate medical attention or contact a poison control center.

Missed Dose

• Take the missed dose as soon as you remember.

• If it is close to the time for the next dose, skip the missed dose.

• Do not double the dose to make up for a missed one.

How To Use

1. Take Zoldap exactly as prescribed by your doctor.

2. Can be taken with or without food.

3. Swallow the tablet whole; do not crush, chew, or split.

4. Continue the medication for the full duration prescribed, even if symptoms improve.

When Not to Use
Do not use Zoldap if you:

• Are allergic to Duloxetine or other SNRIs.

• Are taking monoamine oxidase inhibitors (MAOIs) or have used them in the last 14 days.

• Have uncontrolled narrow-angle glaucoma.

• Have severe liver or kidney impairment (unless specifically prescribed).

Side Effects
Common:

• Nausea, dry mouth, constipation

• Fatigue, dizziness, or headache

• Sweating or insomnia

Serious (seek medical help):

• Severe allergic reactions (rash, swelling, difficulty breathing)

• Liver problems (yellowing of skin/eyes, dark urine)

• Suicidal thoughts or unusual changes in mood or behavior

• High blood pressure or rapid heartbeat

Precautions & Warnings

• Use with caution in patients with liver, kidney, or heart problems.

• Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

• Avoid abrupt discontinuation; taper under doctor supervision to prevent withdrawal symptoms.

• May interact with alcohol or other CNS depressants.

Drug Interactions

• MAO inhibitors (risk of serotonin syndrome)

• Other antidepressants (SSRIs, SNRIs, tricyclics)

• Warfarin (may increase bleeding risk)

• Drugs affecting liver metabolism (CYP1A2 and CYP2D6 inhibitors)

Storage/Disposal

• Store below 30°C in a cool, dry place.

• Keep out of reach of children.

• Dispose of unused or expired medicine safely according to local regulations.

Control Drug
No – Not a controlled substance.

Quick Tips

• Take at the same time each day for consistent effects.

• Avoid skipping doses to maintain mood stabilization.

• Do not abruptly stop the medication.

• Monitor mood changes and report any severe side effects to your doctor.

• Avoid alcohol to reduce liver strain and side effects.