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Provas Duo (500/200mg) is a combination antibiotic medication used to treat bacterial infections in various parts of the body, including the respiratory tract, skin, bones, joints, and urinary tract. It contains two active ingredients — Sulfamethoxazole and Trimethoprim — that work together to stop bacterial growth and eliminate infection.
Ingredients
Active Ingredients:
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Sulfamethoxazole 500 mg
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Trimethoprim 200 mg
Inactive Ingredients:
Lactose monohydrate, starch, magnesium stearate, and other excipients.
Drug Class
Antibiotic (Sulfonamide Combination)
Dosage Form
Oral Tablet
Uses
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Treatment of respiratory tract infections (such as bronchitis and pneumonia)
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Urinary tract infections (UTIs)
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Gastrointestinal infections (such as traveler’s diarrhea or typhoid fever)
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Skin and soft tissue infections
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Ear and sinus infections
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Certain forms of meningitis and toxoplasmosis (as prescribed by a doctor)
Dosage
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Adults: Usually 1 tablet (500/200 mg) every 12 hours or as prescribed by the doctor.
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Duration and dose depend on the type and severity of infection.
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Take for the full prescribed course, even if symptoms improve early.
In case of Overdose
Symptoms may include nausea, vomiting, confusion, dizziness, or blood-related complications.
Seek immediate medical attention or contact a poison control center if overdose occurs.
Missed Dose
If you miss a dose, take it as soon as you remember.
If it’s almost time for your next dose, skip the missed one — do not double the dose.
How To Use
Take the tablet orally with a full glass of water, with or after meals to reduce stomach upset.
Drink plenty of fluids during treatment to prevent kidney stones.
Follow the full course as directed by your physician — stopping early can cause the infection to return or lead to resistance.
When Not to Use
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If allergic to Sulfamethoxazole, Trimethoprim, or other sulfonamide antibiotics
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In patients with severe liver or kidney disease
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In infants under 2 months of age
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During pregnancy or breastfeeding (unless directed by a doctor)
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In patients with a history of blood disorders like anemia caused by folate deficiency
Side Effects
Common: Nausea, vomiting, loss of appetite, mild skin rash, or headache
Less common: Diarrhea, dizziness, or fatigue
Serious (rare): Severe allergic reaction, difficulty breathing, jaundice, or blood disorders
Precautions & Warnings
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Use only under medical supervision.
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Drink plenty of water to prevent crystalluria (crystals in urine).
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Avoid excessive sunlight or tanning beds; this medicine may increase sun sensitivity.
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Regular blood tests may be required if used long-term.
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Inform your doctor about any history of liver, kidney, or blood disorders.
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Stop use and contact your doctor immediately if you develop rash, sore throat, or fever.
Drug Interactions
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Warfarin and other blood thinners – may increase bleeding risk.
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Methotrexate – increases toxicity risk.
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Phenytoin – increases side effects.
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Diuretics – may increase potassium or cause kidney issues.
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Oral diabetes medicines – may cause low blood sugar.
Storage/Disposal
Store below 25°C in a dry place, away from moisture and direct sunlight.
Keep out of reach of children.
Do not use after the expiry date.
Dispose of unused medicine according to local pharmaceutical waste guidelines.
Control Drug
Prescription-only medicine. Not a controlled drug.
Quick Tips
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Take with plenty of fluids to protect your kidneys.
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Complete the full course, even if you feel better.
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Avoid direct sunlight; use sunscreen if needed.
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Report any skin rash, fever, or unusual bleeding to your doctor immediately.
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Do not self-medicate or share this medicine with others.