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Pyloclar (500mg) is an antibiotic medication containing Clarithromycin, used to treat a wide range of bacterial infections. It is especially effective against infections of the respiratory tract, skin, and soft tissues, and is also used as part of combination therapy for eradicating Helicobacter pylori (H. pylori) bacteria that cause peptic ulcers. It works by stopping bacterial growth and eliminating infection from the body.
Ingredients
Active Ingredient: Clarithromycin 500 mg
Inactive Ingredients: Microcrystalline cellulose, croscarmellose sodium, magnesium stearate, povidone, and other excipients.
Drug Class
Macrolide Antibiotic
Dosage Form
Oral Tablet
Uses
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Treatment of respiratory tract infections (bronchitis, pneumonia, sinusitis, pharyngitis)
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Skin and soft tissue infections
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Ear infections (otitis media)
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In combination therapy for H. pylori eradication in peptic ulcer disease
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Certain throat or tonsil infections caused by susceptible bacteria
Dosage
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Adults: Usually 250–500 mg twice daily for 7–14 days, depending on the infection type and severity.
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For H. pylori eradication: Commonly used as part of triple therapy with other antibiotics and a proton pump inhibitor (PPI) for 7–14 days.
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Always follow your doctor’s instructions carefully and complete the full course, even if symptoms improve early.
In case of Overdose
Symptoms may include nausea, vomiting, abdominal pain, or diarrhea.
Seek immediate medical help or contact your nearest healthcare facility in case of overdose.
Missed Dose
If you forget a dose, take it as soon as you remember.
If it’s almost time for your next dose, skip the missed dose. Do not double the dose to make up for the missed one.
How To Use
Take Pyloclar tablets orally with a full glass of water.
It may be taken with or without food, but taking it after meals can reduce stomach discomfort.
Swallow the tablet whole—do not crush or chew.
Follow the prescribed dosage schedule strictly and avoid skipping doses.
When Not to Use
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If allergic to Clarithromycin, other macrolide antibiotics (e.g., erythromycin, azithromycin), or any ingredient in the tablet
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If you have severe liver disease or kidney impairment
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If taking medications such as pimozide, ergot alkaloids, cisapride, or certain cholesterol-lowering drugs (statins)
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During pregnancy or breastfeeding unless prescribed by a doctor
Side Effects
Common: Nausea, vomiting, diarrhea, stomach pain, headache, altered taste
Less common: Dizziness, indigestion, or mild rash
Serious (rare): Liver dysfunction, severe allergic reaction, irregular heartbeat, or hearing changes
Precautions & Warnings
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Use only under medical supervision.
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Inform your doctor if you have liver, kidney, or heart problems.
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Do not combine with other strong antibiotics unless advised by your doctor.
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Avoid alcohol during the course of therapy.
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Use with caution in patients taking medications that prolong QT interval (can affect heart rhythm).
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Complete the full treatment course to prevent antibiotic resistance.
Drug Interactions
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Statins (e.g., simvastatin, lovastatin) – risk of muscle injury (rhabdomyolysis)
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Warfarin – may increase bleeding risk
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Digoxin – may increase digoxin levels
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Theophylline – may increase toxicity
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Antiepileptics and antifungals – may alter drug effectiveness
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Other macrolides or strong antibiotics – avoid co-administration unless advised
Storage/Disposal
Store below 30°C in a cool, dry place away from sunlight and moisture.
Keep out of reach of children.
Do not use after expiry date.
Dispose of unused medicine according to local regulations.
Control Drug
Prescription-only medicine. Not a controlled drug.
Quick Tips
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Take the medicine at the same time each day for best results.
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Complete the full course as directed, even if you start feeling better.
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Avoid skipping doses to prevent antibiotic resistance.
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Take with food to minimize stomach upset.
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Inform your doctor about all medicines you are taking to avoid interactions.