Co-Purpal 500/20mg Tablets (28’s) – Paracetamol & Codeine Phosphate for Moderate Pain Relief

Description:

Co-Purpal 500/20mg Tablets combine Paracetamol (500mg) and Codeine Phosphate (20mg) to provide effective relief from moderate to severe pain that is not adequately controlled by paracetamol or ibuprofen alone.

This dual-action formula works by:

• Paracetamol: reducing pain and fever by acting on the brain’s pain centers.

• Codeine: a mild opioid that enhances pain relief by acting on the central nervous system.

Co-Purpal is commonly prescribed for short-term relief of pain associated with headaches, toothache, period pain, muscle aches, back pain, and post-surgical discomfort.

Ingredients:

Each tablet contains:

• Paracetamol – 500 mg

• Codeine Phosphate Hemihydrate – 20 mg

Inactive ingredients: Maize starch, povidone, stearic acid, talc, and microcrystalline cellulose.

Drug Class:

• Analgesic (Opioid and Non-opioid Combination)

Dosage Form:

• Tablet

Uses:

Co-Purpal is indicated for short-term relief of:

• Moderate pain not relieved by non-opioid painkillers

• Dental pain

• Migraine or tension headache

• Menstrual cramps

• Musculoskeletal pain (e.g., backache, joint pain)

• Post-operative pain

Dosage:

• Adults: 1–2 tablets every 4 to 6 hours as needed.

• Do not exceed 8 tablets in 24 hours.

• Children (under 12 years): Not recommended.

• Use for short durations only (up to 3 days) unless prescribed by a doctor.

Always follow your healthcare provider’s dosage instructions.

In Case of Overdose:

Overdose Warning: Serious or fatal liver damage may occur due to paracetamol overdose.
Symptoms include:

• Nausea, vomiting

• Loss of appetite

• Sweating

• Confusion or drowsiness

👉 Seek emergency medical attention immediately if overdose is suspected — even if you feel well.

Missed Dose:

• Take as soon as you remember if pain persists.

• Skip if it’s almost time for the next scheduled dose.

• Do not double the dose to make up for a missed one.

How To Use:

1. Swallow tablets whole with water.

2. Take with or after meals to reduce stomach upset.

3. Do not exceed the recommended dose.

4. Avoid alcohol or sedative drugs while using this medicine.

5. Intended for short-term use only.

When Not to Use:

Do not use Co-Purpal if you:

• Are allergic to paracetamol, codeine, or other opioids.

• Have severe respiratory depression or asthma attacks.

• Have acute liver disease or chronic alcoholism.

• Are younger than 12 years or breastfeeding (risk of morphine toxicity in infants).

• Have recently taken MAO inhibitors (within 14 days).

Side Effects:

Common side effects:

• Drowsiness or dizziness

• Constipation

• Nausea or vomiting

• Dry mouth

Less common:

• Lightheadedness

• Sweating

• Stomach upset

Serious (seek medical help):

• Difficulty breathing or shallow breathing

• Yellowing of skin/eyes (liver damage)

• Confusion, severe drowsiness

• Allergic reactions (rash, swelling, itching)

Precautions & Warnings:

• This medicine contains an opioid (Codeine) — may cause dependence or addiction if used long-term.

• Avoid alcohol; it increases drowsiness and liver toxicity risk.

• Do not drive or operate heavy machinery after taking it.

• Use cautiously in patients with liver, kidney, or breathing problems.

• Pregnancy & lactation: Only under medical supervision.

• Avoid combining with other medicines containing paracetamol.

Drug Interactions:

Co-Purpal may interact with:

• Other CNS depressants (alcohol, sedatives, antihistamines)

• MAO inhibitors, SSRIs, tricyclic antidepressants

• Anticonvulsants (phenytoin, carbamazepine) – may increase liver toxicity risk

• Anticoagulants (warfarin) – may alter bleeding risk

Always inform your doctor about any other medicines or supplements you take.

Storage/Disposal:

• Store below 30°C, in a cool and dry place.

• Protect from moisture and sunlight.

• Keep out of reach of children.

• Dispose of unused tablets properly — do not flush in the toilet.

Control Drug:

• Controlled Substance (Opioid Analgesic)

• Prescription Only (Rx)

Quick Tips:

• For short-term pain relief only — do not use longer than 3 days without advice.

• Avoid driving or alcohol — may cause sedation.

• Stay hydrated and increase dietary fiber to prevent constipation.

• Do not take with other paracetamol-containing medicines.

• Stop immediately and consult your doctor if you notice yellowing of the skin or dark urine.