Description:
Darvin 37.5/325mg Tablets combine Tramadol Hydrochloride (37.5mg) and Paracetamol (325mg) to provide powerful, dual-action pain relief for moderate to severe pain.
This combination works by targeting pain through two mechanisms:
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Tramadol, an opioid analgesic, alters pain perception in the brain.
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Paracetamol (Acetaminophen) helps reduce pain and fever.
Darvin is prescribed for pain caused by injury, surgery, arthritis, nerve pain, or musculoskeletal conditions. It offers effective relief while minimizing the need for higher opioid doses.
Ingredients:
Each tablet contains:
Inactive ingredients: Lactose monohydrate, microcrystalline cellulose, povidone, magnesium stearate, and other excipients.
Drug Class:
Dosage Form:
Uses:
Darvin is used for short-term management of:
Dosage:
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Adults: Usually 1–2 tablets every 4–6 hours as needed, not exceeding 8 tablets in 24 hours.
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Children: Not recommended under 12 years of age.
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Elderly: Use with caution; consult your doctor for dose adjustment.
⚠️ Always follow your physician’s advice. Do not take for longer than prescribed.
In Case of Overdose:
Overdose can be life-threatening. Symptoms may include:
👉 Seek emergency medical help immediately in case of suspected overdose.
Missed Dose:
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Take the missed dose as soon as you remember if needed for pain.
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Skip it if your next dose is due soon.
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Do not double the dose to make up for a missed one.
How To Use:
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Take orally with water, with or without food.
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Do not exceed the maximum recommended dose.
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Take only when pain relief is needed.
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Avoid alcohol and sedatives while using Darvin.
When Not to Use:
Do not use Darvin if you:
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Are allergic to Tramadol, Paracetamol, or any excipients.
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Have severe liver or kidney disease.
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Suffer from severe respiratory depression or asthma attacks.
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Have recently consumed alcohol, sedatives, or narcotics.
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Are using MAO inhibitors (or within 14 days of stopping them).
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Are pregnant or breastfeeding, unless prescribed by a doctor.
Side Effects:
Common:
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Dizziness or drowsiness
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Nausea or vomiting
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Constipation
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Headache
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Dry mouth
Serious (seek medical help):
Precautions & Warnings:
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May cause drowsiness — avoid driving or operating heavy machinery.
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Avoid alcohol; it increases the risk of side effects.
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Use cautiously in elderly or respiratory-compromised patients.
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Long-term or excessive use may cause dependence or liver toxicity.
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Inform your doctor if you have seizure disorders or head injuries.
Drug Interactions:
Darvin may interact with:
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MAO inhibitors, SSRIs, or antidepressants – risk of serotonin syndrome
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Sedatives, alcohol, or benzodiazepines – may cause respiratory depression
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Warfarin – may increase bleeding risk
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Carbamazepine, phenytoin, or rifampicin – may reduce effectiveness
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Other Paracetamol-containing products – increases risk of liver damage
Always inform your doctor about all other medicines or supplements you are taking.
Storage/Disposal:
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Store below 30°C in a cool, dry place.
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Keep out of reach of children.
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Do not use beyond expiry date.
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Dispose of properly — do not flush down the toilet.
Control Drug:
Quick Tips:
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Take only when needed for pain, and not for longer than prescribed.
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Avoid alcohol and other CNS depressants.
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Do not drive after taking the medicine until you know its effects on you.
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Report any signs of liver issues, confusion, or allergic reaction immediately.
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Never share this medication with others.
