Genticyn 40mg Injection (Gentamicin Sulfate) – 2ml Ampoule | Powerful Aminoglycoside Antibiotic

Description

Genticyn (40mg/2ml) Injection contains Gentamicin Sulfate, a broad-spectrum aminoglycoside antibiotic used for the treatment of serious bacterial infections. It works by stopping bacterial growth and is especially effective against severe infections that do not respond to other antibiotics.

This injection is usually administered in hospitals by trained healthcare professionals either intramuscularly (IM) or intravenously (IV).

Ingredients

• Active Ingredient: Gentamicin Sulfate (40mg/2ml)

• Inactive Ingredients: Sterile water for injection and stabilizing agents

Drug Class

• Aminoglycoside Antibiotic

Dosage Form

• Injection (Ampoule, 2ml containing 40mg gentamicin)

Uses

Genticyn is prescribed for the treatment of:

• Severe urinary tract infections (UTIs)

• Respiratory tract infections (pneumonia, bronchitis)

• Skin and soft tissue infections

• Bone and joint infections

• Abdominal infections (peritonitis, sepsis)

• Septicemia (bloodstream infections)

• Meningitis (caused by susceptible organisms)

• Post-surgical infections

Dosage

• Adults: 3–5 mg/kg body weight per day in divided doses (IM or IV).

• Children: 3–5 mg/kg/day in divided doses.

• Neonates & Premature Infants: 2–5 mg/kg/day.

• Duration: Depends on infection severity, usually 7–10 days.

• Must be administered strictly under doctor’s supervision.

In Case of Overdose

• Symptoms: Hearing loss, balance problems, kidney damage, breathing difficulties.

• Action: Seek immediate emergency medical help.

Missed Dose

• Take the missed dose as soon as remembered if still on schedule.

• Do not double dose.

• Inform healthcare provider if multiple doses are missed.

How To Use

• Administered intramuscularly (IM) or intravenously (IV).

• Must be given by a doctor or trained nurse only.

• Dose and duration depend on infection severity and kidney function.

When Not to Use

Avoid Genticyn if:

• You are allergic to Gentamicin or other aminoglycosides.

• You have severe kidney problems without dose adjustment.

• You have hearing or balance disorders.

• You are pregnant (unless prescribed as life-saving treatment).

Side Effects

Common:

• Injection site pain

• Nausea, vomiting, diarrhea

• Rash or mild allergic reaction

Serious (seek urgent care):

• Hearing loss or ringing in the ears

• Dizziness, balance problems

• Kidney damage (reduced urine output, swelling)

• Severe allergic reaction (swelling, difficulty breathing)

Precautions & Warnings

• Use with caution in elderly patients, newborns, and those with kidney disease.

• Regular monitoring of kidney function and hearing is required during therapy.

• Long-term use may increase the risk of secondary infections.

• Not recommended during pregnancy unless no alternatives are available.

• Breastfeeding mothers should consult a doctor before use.

Drug Interactions

Genticyn may interact with:

• Other aminoglycosides (amikacin, tobramycin)

• Vancomycin (increases kidney toxicity risk)

• Amphotericin B (kidney damage risk)

• Diuretics like furosemide (hearing damage risk)

• Muscle relaxants (may increase muscle weakness)

Storage/Disposal

• Store below 25°C, away from light and heat.

• Do not freeze.

• Keep out of reach of children.

• Dispose of used ampoules safely as per hospital/clinic guidelines.

Control Drug

• Not a controlled substance

• Prescription-only medicine (Rx)

Quick Tips

• Always complete the prescribed course even if symptoms improve.

• Drink plenty of fluids to protect kidneys.

• Report any hearing changes or dizziness immediately.

• Do not self-inject; must be given by a healthcare professional.

• Inform your doctor about kidney, hearing, or balance issues before starting.