Hyzonate 100mg Injection (Hydrocortisone Sodium Succinate) – Corticosteroid for Inflammation, Allergy & Adrenal Crisis

Description

Hyzonate 100mg Injection contains Hydrocortisone Sodium Succinate, a fast-acting corticosteroid used to treat inflammation, severe allergies, asthma, arthritis, adrenal insufficiency, and life-threatening conditions such as anaphylaxis, shock, and adrenal crisis.

It works by reducing inflammation, suppressing the immune system, and replacing the natural cortisol in patients with adrenal insufficiency. The injection is given by intravenous (IV) or intramuscular (IM) route, usually under medical supervision.

Ingredients

• Active Ingredient: Hydrocortisone Sodium Succinate (100mg)

• Inactive Ingredients: Buffers and sterile water for injection

Drug Class

• Corticosteroid / Glucocorticoid

Dosage Form

• Injection (Vial, 100mg)

Uses

Hyzonate 100mg Injection is used for the treatment of:

• Adrenal insufficiency (Addison’s disease, adrenal crisis)

• Severe allergic reactions (anaphylaxis)

• Asthma attacks & COPD exacerbations

• Rheumatic disorders (arthritis, lupus, joint inflammation)

• Severe skin & autoimmune diseases

• Endocrine disorders needing steroid replacement

• Shock (septic shock, trauma, or post-surgery)

• Inflammatory bowel disease (ulcerative colitis, Crohn’s disease)

Dosage

• Adults:

  • Initial: 100mg IV or IM injection.

  • Maintenance: May repeat every 6–8 hours depending on condition.

• Children:

  • Dosage is weight-based (typically 0.56–8mg/kg/day).

• Always follow doctor’s prescription and hospital protocol.

In Case of Overdose

• Symptoms: Mood swings, high blood pressure, high blood sugar, electrolyte imbalance.

• Immediate medical help is required.

Missed Dose

• Since it’s usually given in hospitals, missed doses are rare.

• If self-administering, take as soon as remembered. Do not double the dose.

How To Use

• Administered only by IV or IM injection under medical supervision.

• Not for casual or self-use unless prescribed and trained.

• Follow doctor’s instructions carefully.

When Not to Use

Do not use Hyzonate 100mg if:

• You are allergic to hydrocortisone or other corticosteroids

• You have systemic fungal infections (unless directed by doctor)

• You are receiving live vaccines during treatment

• You have untreated bacterial or viral infections without proper medication

Side Effects

Common:

• Pain or swelling at injection site

• Increased appetite and weight gain

• Indigestion, nausea

• Mood changes (anxiety, irritability)

Serious:

• High blood pressure, high blood sugar

• Vision issues (glaucoma, cataracts)

• Muscle weakness, bone loss (osteoporosis)

• Fluid retention (swelling of face/feet)

• Higher risk of infections

Precautions & Warnings

• Caution in patients with diabetes, hypertension, heart disease, kidney/liver disease, and osteoporosis.

• Long-term therapy should not be stopped suddenly; taper gradually.

• Avoid exposure to people with chickenpox or measles.

• Pregnant or breastfeeding women should consult doctor before use.

Drug Interactions

• NSAIDs (ibuprofen, aspirin – ↑ risk of ulcers)

• Diuretics (low potassium risk)

• Antidiabetics (reduced effect, ↑ blood sugar)

• Live vaccines (risk of infection)

• Antifungals (ketoconazole ↑ steroid levels)

• Anticonvulsants (phenytoin, carbamazepine ↓ steroid effect)

Storage/Disposal

• Store below 25°C, away from heat and direct light.

• Do not freeze.

• Keep out of reach of children.

• Safely discard unused vials as per pharmacist’s advice.

Control Drug

• Not a controlled substance

• Prescription-only medicine (Rx)

Quick Tips

• Do not stop the injection suddenly; taper dose under medical advice.

• Always carry a steroid card/ID if on long-term corticosteroid therapy.

• Take calcium & vitamin D to protect bone health.

• Monitor blood sugar, blood pressure, and weight during therapy.

• Inform doctor before any vaccination or surgery.