Moxiget (400mg/250ml) IV Infusion – Moxifloxacin Injection | 1 Vial

Description

Moxiget IV Infusion contains Moxifloxacin, a fourth-generation fluoroquinolone antibiotic with broad-spectrum activity. It works by blocking bacterial DNA replication enzymes (DNA gyrase and topoisomerase IV), thereby stopping bacterial growth. It is commonly used in hospitals for serious infections when oral treatment is not possible.

Ingredients

• Active Ingredient: Moxifloxacin 400mg

• Excipients: Sodium chloride, water for injection, stabilizers

Drug Class

• Fluoroquinolone Antibiotic

Dosage Form

• Intravenous (IV) Infusion

• Strength: 400mg/250ml

• Single-use vial

Uses / Indications

• Community-acquired pneumonia

• Acute bacterial sinusitis and chronic bronchitis exacerbations

• Complicated skin and soft tissue infections

• Intra-abdominal infections (often in combination therapy)

• Complicated urinary tract infections

• Alternative in patients unable to take oral antibiotics

Dosage

💉 Adult Dose (IV Infusion):

• 400mg once daily, infused over at least 60 minutes

• Treatment duration: 5–14 days depending on infection type

⚠️ No dose adjustment needed for renal impairment, but caution advised in liver dysfunction.

In Case of Overdose

• Symptoms: QT interval prolongation, nausea, dizziness, seizures

• Treatment: Supportive care, ECG monitoring, IV fluids

• Hemodialysis not effective in removing moxifloxacin

Missed Dose

• Administer as soon as possible if missed

• Skip if time for next dose is near

• Do not double infusions to compensate

How To Use

• For hospital or clinical use only

• Administered as slow IV infusion over 60 minutes

• Do not inject IM or give as IV bolus

• Ensure proper hydration during treatment

When Not to Use / Contraindications

• Known hypersensitivity to moxifloxacin or other quinolones

• Patients with QT prolongation, arrhythmias, or uncorrected electrolyte imbalance

• Children, adolescents, pregnant or breastfeeding women (safety not established)

• Severe hepatic impairment

Side Effects

Common:

• Nausea, diarrhea, abdominal discomfort

• Headache, dizziness

• Injection site pain

Serious:

• QT prolongation → arrhythmias

• Tendon inflammation or rupture

• Peripheral neuropathy (tingling, numbness)

• CNS effects (confusion, hallucinations, seizures)

• Severe allergic reactions (rash, anaphylaxis)

• Clostridium difficile-associated diarrhea

Precautions & Warnings

• Avoid prolonged sun exposure (photosensitivity risk)

• Stop treatment if tendon pain or severe rash develops

• Use with caution in elderly or cardiac patients

• Monitor ECG if patient is on other QT-prolonging medicines

• Inform doctor if experiencing mood or nerve-related symptoms

Drug Interactions

• Antiarrhythmic drugs, macrolides, tricyclic antidepressants: Risk of QT prolongation

• NSAIDs: May increase risk of seizures

• Corticosteroids: Higher risk of tendon rupture

• Antacids, iron, zinc supplements: Reduce absorption (avoid concurrent use)

Storage / Disposal

• Store at below 25°C

• Protect from light and freezing

• Use immediately after opening

• Dispose of unused solution safely

Control Drug / Prescription Status

• Prescription-only medicine (Rx)

• Not classified as a controlled substance

Quick Tips

• Always complete the full course even if symptoms improve early

• Drink adequate water to prevent dehydration

• Avoid alcohol and unnecessary sun exposure during treatment

• Inform doctor of all current medicines before starting therapy

• Seek urgent care if irregular heartbeat, tendon pain, or severe rash occurs