Mylaxon 500 µg Injection (Mecobalamin) — 10 Ampoules

Description

Mylaxon is an injectable form of mecobalamin (also known as methylcobalamin, an active form of vitamin B12). It is used when rapid replenishment of B12 is needed, especially in cases of deficiency, neuropathy, or conditions where oral absorption is impaired.

Ingredients

• Active ingredient: Mecobalamin 500 µg (0.5 mg) per ampoule

• Excipients: Sterile water or buffer (as per manufacturer), stabilizers (check the specific product leaflet)

Drug Class

• Vitamin / Nutritional supplement

• Form of Vitamin B12 (cobalamin analog)

Dosage Form

• Sterile injection (solution)

• Supplied in ampoules (each 1 mL, 500 µg)

• Pack contains 10 ampoules

Uses / Indications

Mylaxon injection is used for:

• Treatment of vitamin B12 deficiency, pernicious anemia, or megaloblastic anemia due to B12 deficiencyTreatment of peripheral neuropathy / neuropathic pain / nerve disorders (adjunct therapy) 

• Situations where oral B12 is ineffective or malabsorption exists

Dosage

• Usual dose: 500 µg (1 ampoule) IM or IV (as per physician’s instruction)

• Often given daily or alternate days initially, then maintenance doses weekly or monthly depending on the patient’s B12 levels and condition.

• Adjust according to response, B12 levels, and clinical condition.

In Case of Overdose

• Vitamin B12 has very low toxicity, so overdose is rare.

• Symptoms of very high B12 may include mild diarrhea, itching, rash, or injection-site effects.

• Management is supportive.

Missed Dose

• Administer as soon as remembered, unless close to next scheduled dose.

• Do not double the next dose.

How To Use / Administration

1. Inspect the ampoule: solution should be clear and free from particulates.

2. Use aseptic technique to open ampoule and draw up the dose with a sterile syringe.

3. Administer intramuscular (IM) or intravenous (IV) route as directed by the physician.

4. After injection, apply gentle pressure; avoid rubbing the site.

When Not to Use / Contraindications

• Hypersensitivity to cobalamin, cobalt, or any component of the product.

• Uncontrolled Leber’s disease (optic nerve atrophy) — may worsen the condition. 

Side Effects / Adverse Reactions

Common / mild:

• Injection-site pain or irritation

• Mild rash, itching

• Headache, nausea in rare cases 

Rare / serious:

• Hypersensitivity reactions (rash, swelling, anaphylaxis)

• Diarrhea, dizziness, general malaise (rare)

• Flushing

Precautions & Warnings

• In patients with renal impairment, monitor closely.

• Use caution in cases of polycythemia (elevated red cell mass).

• Ensure that folate deficiency is not present alone (address both B12 and folate if needed).

• Monitor for improvement in blood parameters and neurological symptoms.

Drug Interactions

• Folate / folic acid supplementation: may mask B12 deficiency if used alone (but less relevant in injection scenario).

• Certain antibiotics / drugs: e.g. colistin, neomycin, metformin, proton pump inhibitors may reduce GI absorption of B12 (less relevant for injections).

• Always check coadministered medications for interactions during oral therapy; injection route bypasses GI absorption issues.

Storage / Disposal

• Store as per label (typically at controlled room temperature, away from direct sunlight).

• Do not freeze.

• Protect from light and moisture.

• Dispose of used ampoules / needles in sharps containers per medical waste disposal protocols.

Control Drug / Prescription Status

• Prescription-only (requires medical oversight)

• Administered only by or under supervision of qualified healthcare professional.

Quick Tips

• Always measure B12 levels (serum B12, methylmalonic acid, homocysteine) before and during therapy.

• Use the injection in conjunction with oral supplementation or diet when possible.

• Monitor neurological function (sensory symptoms, nerve pain) during therapy.

• Keep a record of administration date, batch, and patient response.

• Educate patients on follow-up and signs of allergic reaction or side effects.