Description
Oxidil (250mg) IM Injection contains Cefotaxime Sodium, a third-generation cephalosporin antibiotic. It is widely used in the treatment of serious bacterial infections by inhibiting bacterial cell wall synthesis, which leads to bacterial cell death. This injection is administered intramuscularly and is effective against a wide range of Gram-positive and Gram-negative bacteria.
Ingredients
Drug Class
Antibiotic – Third-Generation Cephalosporin
Dosage Form
Injection – Powder for reconstitution (Intramuscular)
Uses
Oxidil is prescribed for:
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Respiratory tract infections (bronchitis, pneumonia)
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Urinary tract infections (UTIs)
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Skin and soft tissue infections
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Intra-abdominal infections
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Bone and joint infections
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Septicemia (bloodstream infections)
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Meningitis (bacterial)
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Post-surgical infections
Dosage
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Adults: 1–2g every 8–12 hours (dose depends on infection severity).
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Children: 50–100 mg/kg/day divided into 2–4 doses.
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Must be administered intramuscularly by a healthcare professional.
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Always follow the exact prescription of your doctor.
In case of Overdose
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Symptoms: Seizures, confusion, severe diarrhea, electrolyte imbalance.
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Management: Supportive treatment and monitoring of vital functions.
Missed Dose
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In hospital settings, doses are rarely missed.
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If missed, it should be given as soon as possible under medical supervision.
How To Use
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Reconstitute powder with sterile water for injection.
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Administer deep intramuscularly by a trained healthcare provider.
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Do not self-administer without medical guidance.
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Complete the full antibiotic course to avoid resistance.
When Not to Use
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Allergy to cefotaxime, cephalosporins, or penicillin derivatives.
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Patients with a history of severe hypersensitivity reactions to beta-lactam antibiotics.
Side Effects
Common:
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Pain or swelling at injection site
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Diarrhea, nausea, vomiting
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Mild rash, headache
Serious (rare):
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Severe allergic reactions (anaphylaxis)
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Clostridium difficile-associated diarrhea
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Blood disorders (low platelets, anemia)
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Seizures (especially with renal impairment or overdose)
Precautions & Warnings
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Use with caution in patients with kidney or liver impairment.
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Inform your doctor if you are pregnant or breastfeeding.
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Long-term use may lead to secondary infections (fungal or resistant bacteria).
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Monitor patients with a history of gastrointestinal issues (e.g., colitis).
Drug Interactions
May interact with:
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Aminoglycosides (increased risk of nephrotoxicity)
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Diuretics like furosemide (increased kidney strain)
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Anticoagulants (warfarin – increased bleeding risk)
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Probenecid (increases cefotaxime blood levels)
Storage/Disposal
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Store below 25°C in a cool, dry place.
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Protect from direct light and moisture.
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Use freshly reconstituted solution immediately.
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Dispose of unused vials and syringes according to medical waste regulations.
Control Drug
Prescription-only medicine (not a controlled substance).
Quick Tips
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Do not stop treatment early, even if symptoms improve.
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Inform your doctor about allergies to antibiotics before use.
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Report severe diarrhea or skin reactions immediately.
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Drink plenty of fluids during treatment to support kidney function.
