Rocephin 1g IM Injection – Broad-Spectrum Antibiotic | Ceftriaxone

Description

Rocephin (1g) Intramuscular Injection contains Ceftriaxone, a third-generation cephalosporin antibiotic. It works by killing or stopping the growth of bacteria responsible for various serious infections. Rocephin is widely used in hospitals and clinics for treating severe bacterial infections, including pneumonia, urinary tract infections, skin infections, meningitis, and gonorrhea.

Ingredients

• Active Ingredient: Ceftriaxone Sodium (1g)

• Inactive Ingredients: Sterile water for injection (diluent)

Drug Class

• Third-Generation Cephalosporin Antibiotic

Dosage Form

• Injection (Intramuscular)

• Strength: 1g vial

Uses

• Severe bacterial infections such as:

  • Respiratory tract infections (pneumonia, bronchitis)

  • Urinary tract infections (UTIs)

  • Intra-abdominal infections

  • Skin and soft tissue infections

  • Gonorrhea (sexually transmitted infection)

  • Meningitis (infection of brain and spinal cord)

  • Sepsis (blood poisoning)

• Surgical prophylaxis to prevent infections after operations

Dosage

• Adults: 1–2 g once daily or divided into 12-hour doses (depending on infection severity)

• Children & Infants: Dose adjusted according to weight and medical condition
  ⚠️ Must only be given by a healthcare professional

In Case of Overdose

• Symptoms: Seizures, confusion, irregular heartbeat

• Immediate hospital care required

Missed Dose

• If missed, take as soon as remembered

• Skip if close to next scheduled dose

• Do not double dose

How To Use

• Administered by intramuscular (IM) injection by a trained healthcare professional

• Should not be self-administered at home without guidance

When Not to Use

• Known allergy to ceftriaxone, penicillins, or other cephalosporins

• Newborns with high bilirubin levels (risk of kernicterus)

• Patients with severe liver + kidney impairment without monitoring

Side Effects

• Common: Pain at injection site, diarrhea, nausea, headache

• Less common: Rash, dizziness, elevated liver enzymes

• Rare but serious: Severe allergic reactions, jaundice, seizures, Clostridium difficile-associated diarrhea

Precautions & Warnings

• Use with caution in patients with:

  • Kidney or liver disease

  • History of gastrointestinal disease (especially colitis)

  • Allergies to antibiotics

• Can alter blood tests (Coombs test, glucose tests)

• Use in pregnancy and breastfeeding only under medical supervision

Drug Interactions

• Calcium-containing IV solutions → risk of precipitation in lungs/kidneys (in neonates)

• Aminoglycosides (e.g., gentamicin) → ↑ risk of kidney damage

• Blood thinners (warfarin, heparin) → ↑ bleeding risk

• Probenecid → ↑ ceftriaxone levels in blood

Storage/Disposal

• Store below 25°C, away from direct light

• Reconstituted solution should be used immediately or as per hospital guidelines

• Discard unused vials properly via medical waste disposal

Control Drug

• Not a controlled substance

• Prescription required

Quick Tips

• Complete the full course as prescribed, even if you feel better

• Report any persistent diarrhea – may indicate a secondary infection

• Drink plenty of fluids unless restricted by your doctor

• Do not self-inject unless instructed by a healthcare provider