Venofer Injection 100mg/5ml – 5 Ampoules (Iron Sucrose)

Description

Venofer Injection contains Iron Sucrose (100mg/5ml), an intravenous iron preparation used to treat iron deficiency anemia (IDA), especially in patients with chronic kidney disease (CKD) or those who cannot tolerate oral iron supplements. It helps restore iron levels in the body, supporting the production of healthy red blood cells and improving energy, strength, and overall well-being.

Ingredients

• Active Ingredient: Iron Sucrose 100mg/5ml

• Inactive Ingredients: Sodium hydroxide, hydrochloric acid (for pH adjustment), and water for injection

Drug Class

Iron Replacement Therapy

Dosage Form

• Injection (Ampoule – 5ml solution for IV use)

Uses

Venofer is prescribed for:

• Treatment of iron deficiency anemia in patients with:

  • Chronic kidney disease (CKD) on dialysis or not on dialysis

  • Patients who cannot tolerate or respond poorly to oral iron

• Rapid correction of iron deficiency when oral supplements are insufficient

Dosage

• Adults (CKD patients): Dose depends on body weight and severity of anemia. Typically given as 100–200mg (5–10ml) by IV injection 2–3 times per week, adjusted per doctor’s advice.

• Maximum single dose: Usually up to 200mg (10ml) not more than 3 times per week.

• Always administered by a healthcare professional.

In Case of Overdose

• Symptoms: Low blood pressure, nausea, vomiting, dizziness, headache, iron overload, difficulty breathing.

• Treatment: Stop infusion immediately, monitor iron levels, and provide supportive medical care.

Missed Dose

• Since Venofer is usually given in a clinical setting, missed doses are unlikely.

• If missed, the doctor will reschedule as needed – do not self-administer.

How to Use

• Administered intravenously (IV) either as:

  • Slow injection over 2–5 minutes, or

  • Diluted in saline and given as infusion over 15–30 minutes

• Only given under medical supervision in hospitals/clinics.

• Dosage and frequency depend on iron deficiency severity.

When Not to Use

• Allergy to iron sucrose or any component of the injection

• Patients with iron overload disorders (hemochromatosis, hemosiderosis)

• Anemia not caused by iron deficiency (e.g., megaloblastic anemia)

• First trimester of pregnancy unless prescribed by doctor

Side Effects

Common:

• Headache

• Nausea, vomiting

• Metallic taste in mouth

• Dizziness, low blood pressure during infusion

• Injection site pain or swelling

Serious (rare):

• Severe allergic reactions (rash, itching, difficulty breathing)

• Chest pain, palpitations

• Severe hypotension

• Muscle/joint pain

• Anaphylaxis (rare but possible – requires immediate medical attention)

Precautions & Warnings

• Use with caution in patients with asthma, eczema, liver disease, or cardiovascular problems

• Monitor iron levels regularly to avoid iron overload

• Should not be used in children unless specifically prescribed

• Pregnant and breastfeeding women: Use only if clearly required and approved by doctor

• Do not exceed recommended dose to prevent toxicity

Drug Interactions

• Oral iron supplements (not recommended during IV iron therapy)

• ACE inhibitors (risk of increased side effects like low blood pressure)

• Other iron injections → risk of iron overload

• Medications causing hypotension (additive effect possible)

Storage/Disposal

• Store at below 25°C in a cool, dry place

• Keep ampoules in original packaging, protected from light

• Do not freeze

• Use immediately after opening

• Dispose of unused or expired medicine in biomedical waste containers

Control Drug

• Yes – Prescription-only medicine

• Should only be used under medical supervision

Quick Tips

• Do not self-inject; always take under professional care

• You may feel dizziness after infusion – avoid driving immediately after treatment

• Inform your doctor if you have a history of allergies before starting

• Iron levels and hemoglobin should be monitored during therapy

• Continue a balanced diet rich in iron (green leafy vegetables, red meat, beans) to support treatment