Zyloric 300mg Tablets
Zyloric 300mg contains Allopurinol 300mg, a xanthine oxidase inhibitor used to lower high uric acid levels in blood and urine. It helps prevent gout attacks, reduce joint inflammation, protect kidney function, and manage hyperuricemia, including uric acid buildup during cancer therapy.
Ingredients
Active Ingredient: Allopurinol 300mg
Inactive Ingredients: Lactose, starch, magnesium stearate, cellulose, and other excipients.
Drug Class
Class: Xanthine Oxidase Inhibitor
Category: Anti-Gout / Uric Acid Lowering Agent
Dosage Form
Form: Tablet
Strength: 300mg
Pack Size: 30 Tablets
Uses
- Prevention and treatment of gout
- Management of hyperuricemia
- Prevention of uric acid kidney stones
- Reduction of uric acid buildup during chemotherapy
- Prevention of uric acid nephropathy
Dosage
Adults: 300mg once daily or as directed by your doctor. Dose may vary based on uric acid levels and kidney function.
Elderly / kidney-impaired: Lower doses may be prescribed.
Children: Only if prescribed (e.g., cancer therapy).
💊 Take with or after meals with plenty of water. Follow doctor's instructions.
In Case of Overdose
Symptoms: Nausea, vomiting, dizziness, drowsiness.
Action: Seek immediate medical attention.
Missed Dose
- Take as soon as remembered.
- Skip if it is almost time for the next dose.
- Do not double the dose.
How To Use
- Swallow whole with a full glass of water after meals.
- Stay well-hydrated (8–10 glasses/day).
- Take daily at the same time.
- Do not stop suddenly without consulting your doctor.
When Not to Use
- Allergy to Allopurinol or other xanthine oxidase inhibitors
- Severe liver or kidney disease (unless prescribed)
- During an active gout attack
- Pregnancy or breastfeeding unless advised
Side Effects
Common: Skin rash, nausea, vomiting, dizziness, drowsiness, headache, diarrhea
Serious (rare): Severe allergic reactions (rash, peeling skin, fever, sore throat), liver problems (yellowing), kidney problems (changes in urination, lower back pain)
Precautions & Warnings
- Drink plenty of water to prevent kidney stones
- Regularly monitor uric acid, kidney, and liver function
- Avoid alcohol and purine-rich foods (red meat, seafood, organ meats)
- Do not start during an acute gout flare
- May cause drowsiness—avoid driving until reaction is known
- Use with caution with diuretics or ACE inhibitors
Drug Interactions
- Azathioprine, 6-Mercaptopurine – requires dose reduction
- Warfarin – may increase bleeding risk
- Ampicillin or Amoxicillin – may increase rash risk
- Diuretics (Thiazides) – may raise uric acid levels
- Cyclophosphamide – may enhance toxicity
Storage/Disposal
- Store below 30°C in a cool, dry place
- Protect from moisture and sunlight
- Keep out of reach of children
- Do not use after expiry
- Dispose properly—do not flush or throw in household waste
Control Drug
Prescription-only medication (Not a controlled drug).
Quick Tips
- Take regularly, even when feeling well
- Maintain hydration—8–10 glasses/day
- Avoid alcohol and purine-rich foods
- Your doctor may prescribe colchicine or NSAIDs at start to prevent gout attacks
- Report rash, fever, or sore throat immediately
- Do not start during an active gout flare
