Cefstar (500mg) Injection | Broad-Spectrum Cephalosporin Antibiotic

Description

Cefstar (500mg) Injection is a broad-spectrum antibiotic that belongs to the third-generation cephalosporin class. It works by inhibiting bacterial cell wall synthesis, leading to bacterial death. It is effective against a wide variety of infections, including respiratory tract infections, urinary tract infections, skin infections, and septicemia. It is administered under medical supervision, usually in a hospital or clinical setting.

Ingredients

• Active Ingredient: Ceftriaxone Sodium (500mg)

• Excipients: Sterile agents for injection preparation

Drug Class

• Cephalosporin Antibiotic (Third Generation)

Dosage Form

• Injection (Powder for reconstitution)

• Strength: 500mg per vial

Uses / Indications

• Respiratory tract infections (pneumonia, bronchitis)

• Urinary tract infections (UTIs)

• Skin and soft tissue infections

• Intra-abdominal infections

• Bone and joint infections

• Septicemia and meningitis

• Gynecological infections

• Prophylaxis before certain surgeries

Dosage

💉 Dosage is determined by a physician depending on infection severity and patient condition.

• Adults: 1–2g once daily (can be divided into two doses); maximum 4g/day

• Children: 20–80mg/kg daily (dose adjusted by weight and severity)

• Elderly & Renal Impairment: Dose adjustment may be required

In Case of Overdose

• Symptoms: Nausea, vomiting, diarrhea, convulsions, CNS toxicity (rare)

• Management: Symptomatic treatment, supportive care; dialysis may help remove the drug

Missed Dose

• Take the missed dose as soon as remembered

• Skip if it’s close to the next dose

• Do not double the dose

How To Use

• Reconstitute with sterile water or recommended diluent before use

• Administered via intravenous (IV) injection, infusion, or intramuscular (IM) injection

• To be given by trained healthcare professionals only

When Not to Use / Contraindications

• Known hypersensitivity to ceftriaxone, cephalosporins, or penicillins

• Newborns with hyperbilirubinemia (risk of kernicterus)

• Patients with severe allergy history (anaphylaxis) to beta-lactam antibiotics

Side Effects

Common:

• Diarrhea, nausea, vomiting

• Pain, redness, or swelling at injection site

• Mild rash or itching

Serious (rare):

• Severe allergic reactions (anaphylaxis)

• Clostridium difficile–associated diarrhea

• Liver enzyme abnormalities

• Blood disorders (anemia, leukopenia, thrombocytopenia)

Precautions & Warnings

• Use cautiously in patients with liver or kidney dysfunction

• Prolonged use may result in fungal or resistant bacterial superinfection

• Monitor liver and kidney function with prolonged therapy

• Not effective against viral infections (flu, cold)

• Pregnant and breastfeeding women should use only under medical advice

Drug Interactions

• Calcium-containing IV solutions (risk of precipitation with ceftriaxone)

• Warfarin (increased bleeding risk)

• Aminoglycosides (enhanced nephrotoxicity)

• Probenecid (may increase ceftriaxone levels)

Storage / Disposal

• Store below 25°C in a dry place

• Protect from light and moisture

• Use immediately after reconstitution

• Discard unused solution safely

Control Drug / Prescription Status

• Prescription-only medicine

Quick Tips

• Complete the full prescribed course even if symptoms improve early

• Report any severe diarrhea or allergic reaction immediately

• Do not self-inject; must be administered in a clinical or hospital setting

• Stay well-hydrated during treatment