Fortum Injection 250 mg (Ceftazidime) – 1 Vial

Description

Fortum Injection contains Ceftazidime, a third-generation cephalosporin antibiotic. It is used to treat a wide range of severe bacterial infections, especially those caused by Gram-negative organisms including Pseudomonas aeruginosa.

Ingredients

• Active ingredient: Ceftazidime 250 mg (as pentahydrate) per vial

• Excipients: May contain sodium carbonate (to adjust pH)

Drug Class

• Antibiotic – Third-generation cephalosporin

Dosage Form

• Injection / Infusion powder for solution (vial for IM or IV use)

Uses / Indications

Fortum is indicated for treatment of infections caused by susceptible bacteria, including:

• Respiratory tract infections (pneumonia, lung infections in cystic fibrosis)

• Urinary tract infections (complicated cases)

• Skin and soft tissue infections

• Bone and joint infections

• Abdominal infections (peritonitis, biliary tract infections)

• Meningitis (bacterial)

• Septicemia (bloodstream infections)

• Infections in immunocompromised patients (including neutropenic patients)

Dosage (General guidance – individualized by physician)

• Adults: 1–2 g every 8–12 hours IV or IM, depending on severity.

• Children: 30–50 mg/kg every 8 hours.

• Neonates (up to 2 months): 25–60 mg/kg per day in divided doses.

• Renal impairment: Dosage adjustment required.

• Always reconstituted with sterile water or appropriate diluent before use.

In Case of Overdose

• Symptoms: Neurological effects (e.g., seizures, encephalopathy), especially in patients with renal impairment.

• Management: Symptomatic and supportive care; hemodialysis may help remove drug.

Missed Dose

• Administer as soon as possible if missed.

• If close to next dose, skip missed dose — do not double.

How To Use

• Administered by intravenous injection, infusion, or intramuscular injection.

• Must be prepared freshly before administration.

• Given by healthcare professionals in hospital/clinical setting.

When Not to Use (Contraindications)

• Known hypersensitivity to ceftazidime, other cephalosporins, or severe allergic reaction to penicillins.

• Use with caution in patients with a history of severe beta-lactam allergy.

Side Effects

Common:

• Pain or redness at injection site

• Diarrhea, nausea, vomiting

• Rash, itching

Serious (rare):

• Severe allergic reactions (anaphylaxis, angioedema)

• Clostridium difficile–associated diarrhea

• Seizures (especially in renal impairment)

• Blood disorders (leukopenia, thrombocytopenia)

Precautions & Warnings

• Adjust dose in renal impairment to avoid neurotoxicity.

• Monitor for signs of superinfection (fungal or bacterial overgrowth).

• Use cautiously in patients with history of GI disease (especially colitis).

• Monitor blood counts and kidney function during prolonged therapy.

Drug Interactions

• Aminoglycosides: May increase nephrotoxicity risk.

• Loop diuretics (e.g., furosemide): Increased kidney toxicity risk.

• Chloramphenicol: May antagonize cephalosporins’ antibacterial effects.

Storage / Disposal

• Store below 25°C, protected from light and moisture.

• Reconstituted solution should be used immediately (or within manufacturer’s specified timeframe if refrigerated).

• Discard unused portion safely.

Control Drug / Prescription Status

• Prescription-only medicine

• Not available OTC

Quick Tips

• Fortum is a broad-spectrum antibiotic effective against serious infections.

• Complete the prescribed course — do not stop early.

• Inform doctor if you have penicillin/cephalosporin allergy.

• Report persistent diarrhea or unusual bleeding/bruising.

• Dose adjustment is vital in kidney disease to avoid toxicity.