Solu-Medrol 125mg/2ml Injection – Anti-Inflammatory Corticosteroid Vial

Description

Solu-Medrol (125mg/2ml) Injection contains Methylprednisolone Sodium Succinate, a fast-acting corticosteroid medication. It is used for the treatment of inflammation, allergic reactions, asthma attacks, arthritis, severe skin conditions, and autoimmune disorders. Solu-Medrol provides rapid relief in emergency situations like severe allergic reactions and acute exacerbations of chronic diseases.

Ingredients

• Active Ingredient: Methylprednisolone Sodium Succinate (125mg/2ml)

• Inactive Ingredients: Sodium phosphate buffers, water for injection

Drug Class

• Corticosteroid / Glucocorticoid

• Anti-inflammatory and Immunosuppressant

Dosage Form

• Injectable solution (Vial)

• Strength: 125mg/2ml

Uses

• Severe allergic reactions (anaphylaxis, angioedema)

• Asthma and chronic obstructive pulmonary disease (COPD) exacerbations

• Rheumatoid arthritis, osteoarthritis, and severe joint inflammation

• Autoimmune disorders (lupus, multiple sclerosis)

• Skin diseases (eczema, psoriasis, dermatitis)

• Shock due to adrenal insufficiency

• Certain cancers (as supportive therapy)

• Acute inflammation in severe infections (with antibiotics)

Dosage

• Adults & Children: Dose depends on severity and condition; usually administered by IV or IM injection under a doctor’s supervision

• Emergency use: 30mg/kg IV dose may be given in life-threatening cases

• Maintenance dose varies as per medical condition

⚠️ Must be given by a healthcare professional only.

In Case of Overdose

• Symptoms: Confusion, high blood pressure, seizures, mood changes, electrolyte imbalance

• Immediate medical care required

• Supportive treatment provided in hospital

Missed Dose

• If on scheduled therapy, take the dose as soon as remembered

• Skip if it’s almost time for the next dose

• Never double dose

How To Use

1. Administered by intravenous (IV) or intramuscular (IM) injection by a trained professional

2. Dosage adjusted based on disease severity and patient response

3. Do not self-inject without medical guidance

4. Complete prescribed course to avoid withdrawal effects

When Not to Use

• Known allergy to methylprednisolone or other corticosteroids

• Fungal infections (systemic)

• Untreated bacterial or viral infections (unless prescribed with antimicrobials)

• Live vaccines (should not be taken during corticosteroid therapy)

• Caution in patients with peptic ulcer, osteoporosis, uncontrolled diabetes, hypertension

Side Effects

• Common: Headache, nausea, mood swings, increased appetite, injection site irritation

• Serious: High blood pressure, vision changes, irregular heartbeat, severe infections, adrenal suppression, Cushing’s syndrome (long-term use)

Precautions & Warnings

• Use with caution in diabetes, hypertension, heart disease, kidney or liver impairment

• May weaken immune system – avoid exposure to infections (chickenpox, measles, TB)

• Long-term use can cause bone weakness, weight gain, mood changes, and eye problems

• Pregnant or breastfeeding women should use only if clearly needed

• Gradual withdrawal required to prevent adrenal crisis – do not stop suddenly

Drug Interactions

• May interact with:

  • NSAIDs (increased risk of ulcers)

  • Anticoagulants (warfarin)

  • Antifungals (ketoconazole)

  • Anticonvulsants (phenytoin, carbamazepine)

  • Rifampicin (reduces steroid effect)

  • Live vaccines (risk of infection)

Storage/Disposal

• Store below 25°C, away from heat and light

• Do not freeze

• Keep out of reach of children

• Discard unused or expired vials safely as per hospital/clinic guidelines

Control Drug

• Prescription-only medicine

• Not a controlled substance

Quick Tips

• Always follow doctor’s prescribed dose – do not self-medicate

• Avoid abrupt discontinuation after prolonged use

• Monitor blood sugar and blood pressure regularly during treatment

• Carry a medical card stating you are on corticosteroid therapy

• Inform your doctor before any surgery or vaccination