Bepsar Plus 50/12.5mg Tablets – 20 Tablets | Eplerenone + Hydrochlorothiazide | Dual Action for Hypertension & Heart Failure

Description

Bepsar Plus (50/12.5mg) Tablets combine Eplerenone (50mg) and Hydrochlorothiazide (12.5mg) to effectively manage high blood pressure (hypertension) and heart-related fluid retention.
This dual-action formula lowers blood pressure by blocking aldosterone (a hormone that retains salt and water) and promoting mild diuresis (urine production), which helps reduce excess fluid and strain on the heart.
Regular use helps prevent strokes, heart attacks, and kidney complications associated with high blood pressure.

💊 Ingredients

• Active Ingredients:

  • Eplerenone 50mg – Aldosterone antagonist

  • Hydrochlorothiazide 12.5mg – Thiazide diuretic

• Inactive Ingredients:

  • Microcrystalline cellulose

  • Lactose monohydrate

  • Magnesium stearate

  • Hypromellose coating agents

⚕️ Drug Class

• Therapeutic Class: Antihypertensive / Diuretic Combination

• Pharmacological Class:

  • Potassium-sparing diuretic (Eplerenone)

  • Thiazide diuretic (Hydrochlorothiazide)

💊 Dosage Form

• Form: Tablet

• Strength: 50mg/12.5mg

• Pack Size: 20 Tablets

✅ Uses

Bepsar Plus is used for:

• High blood pressure (hypertension)

• Heart failure, particularly post-myocardial infarction (after a heart attack)

• Edema (fluid retention) due to heart or kidney conditions

• Reducing risk of stroke, heart attack, and cardiovascular mortality

💊 Dosage

• Typical Adult Dose:

  • Usually 1 tablet once daily, as prescribed.

• The dosage may vary depending on kidney function, electrolyte levels, and response to treatment.

• Always follow your doctor’s directions precisely.

⚠️ In Case of Overdose

Symptoms may include:

• Severe dizziness or fainting (low blood pressure)

• Muscle weakness or irregular heartbeat (high potassium)

• Excessive urination or dehydration

Action:
Seek immediate medical assistance or visit the nearest emergency room.

⏰ Missed Dose

• Take the missed dose as soon as you remember.

• If it’s almost time for your next dose, skip the missed one.

• Do not double the dose to make up for a missed tablet.

💡 How To Use

• Take orally with or without food.

• Swallow whole with a full glass of water.

• Take at the same time each day to maintain stable blood pressure.

• Continue even if you feel better — stopping abruptly may worsen your condition.

🚫 When Not to Use

Do not use Bepsar Plus if you have:

• Allergy to Eplerenone or Hydrochlorothiazide

• Severe kidney disease or inability to pass urine (anuria)

• High potassium (hyperkalemia)

• Severe liver impairment

• Gout or low sodium/potassium levels

• Concurrent use of strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)

• Pregnancy or breastfeeding (unless approved by doctor)

⚠️ Side Effects

Common Side Effects:

• Dizziness or lightheadedness

• Headache or fatigue

• Increased urination

• Mild muscle cramps

Less Common:

• Dry mouth

• Nausea or stomach discomfort

• Changes in potassium levels

Serious (Seek Medical Help):

• Irregular heartbeat

• Severe dehydration

• Allergic reaction (rash, swelling, breathing difficulty)

⚠️ Precautions & Warnings

• Monitor blood pressure, potassium, and kidney function regularly.

• Avoid salt substitutes or potassium supplements.

• Inform your doctor about any kidney, liver, or heart conditions.

• Use cautiously if diabetic or elderly.

• Avoid prolonged exposure to sunlight — Hydrochlorothiazide may cause photosensitivity.

💊 Drug Interactions

Bepsar Plus may interact with:

• ACE inhibitors / ARBs (e.g., lisinopril, losartan)

• NSAIDs (e.g., ibuprofen, naproxen)

• Potassium supplements

• CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)

• Lithium – may increase lithium toxicity

• Other diuretics or blood pressure medications

🗄️ Storage / Disposal

• Store below 30°C, in a cool and dry place.

• Protect from light and moisture.

• Keep out of reach of children and pets.

• Dispose of expired tablets safely as per pharmacist’s guidance.

🛡️ Control Drug

• Prescription Only (Rx)

• Controlled Substance: No

💡 Quick Tips

• Take at the same time each day to maintain blood pressure control.

• Drink adequate fluids, but avoid excessive salt or potassium-rich foods.

• Rise slowly from sitting/lying positions to prevent dizziness.

• Avoid alcohol — it can enhance drowsiness or lower blood pressure too much.

• Continue medication even if you feel well — hypertension often shows no symptoms.

⚠️ Disclaimer:

This information is for educational purposes only and should not replace professional medical advice. Always follow your doctor’s instructions and use Bepsar Plus under medical supervision.