Insuget R Injection (Regular Human Insulin) 100IU/ml — 10ml Vial

Description

Insuget R contains Regular Human Insulin (100 IU/ml), a short-acting insulin preparation used to control blood glucose in patients with diabetes mellitus. It helps lower blood sugar by facilitating cellular uptake of glucose and is typically administered subcutaneously before meals.

Ingredients

• Active ingredient: Regular Human Insulin 100 IU/ml

• Excipients: Glycerol, metacresol, zinc chloride, sodium phosphate buffer, and water for injection

Drug Class

• Antidiabetic agent

• Short-acting human insulin preparation

Dosage Form

• Injectable solution in 10ml multidose vial

• For subcutaneous (SC) or intravenous (IV) use (under medical supervision)

Uses / Indications

• Management of Type 1 Diabetes Mellitus

• Management of Type 2 Diabetes Mellitus (when oral antidiabetic agents are inadequate)

• Emergency management of diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) (IV use under hospital care)

• Perioperative and hospital glucose control

Dosage

• Individualized based on patient’s blood glucose levels, dietary habits, and physician’s recommendation

• Usually administered 30 minutes before meals

• May be used alone or in combination with intermediate/long-acting insulins

• Typical starting dose: 0.2–0.5 IU/kg/day (split into multiple injections)

In Case of Overdose

• Hypoglycemia (low blood sugar) is the most common effect

• Symptoms: Sweating, tremors, palpitations, headache, confusion, seizures, loss of consciousness

• Management: Oral glucose (mild), IV glucose or glucagon injection (severe cases)

Missed Dose

• If a meal is delayed or skipped, insulin dose should not be taken

• Do not double the dose — take the next dose as advised by your doctor

How To Use

1. Wash hands and prepare injection site (abdomen, thigh, or upper arm)

2. Use a sterile insulin syringe or pen device

3. Inject subcutaneously about 30 minutes before meals

4. Rotate injection sites to avoid lipodystrophy

5. For IV use — only under strict hospital supervision

When Not to Use / Contraindications

• Hypoglycemia (do not inject when blood sugar is already low)

• Allergy to human insulin or excipients

• Caution in patients with kidney or liver impairment

Side Effects

Common:

• Injection site reactions (pain, redness, swelling)

• Hypoglycemia

• Weight gain

Rare/Serious:

• Severe hypoglycemia with loss of consciousness or seizures

• Allergic reactions (rash, swelling, difficulty breathing)

• Lipodystrophy at injection site

Precautions & Warnings

• Regular monitoring of blood glucose is essential

• Dose may need adjustment in cases of illness, surgery, or stress

• Avoid alcohol as it increases the risk of hypoglycemia

• Pregnancy & lactation: Safe under medical guidance, but dose adjustments may be needed

• Caution with heavy exercise — can increase insulin sensitivity

Drug Interactions

• Increased hypoglycemia risk: Oral antidiabetics, beta-blockers, ACE inhibitors, sulfonamides, alcohol

• Reduced insulin effect: Corticosteroids, thiazide diuretics, thyroid hormones, oral contraceptives

• Beta-blockers may mask hypoglycemia warning symptoms

Storage / Disposal

• Store at 2–8°C (refrigerated), do not freeze

• Keep away from direct heat and sunlight

• Open vial may be kept at room temperature (below 25°C) for up to 28 days

• Dispose of used syringes/needles in a proper sharps container

Control Drug / Prescription Status

• Prescription-only medicine

Quick Tips

• Take Insuget R 30 minutes before meals

• Always carry a source of fast-acting sugar (glucose tablets, juice) in case of hypoglycemia

• Rotate injection sites to avoid skin changes

• Never stop insulin suddenly without medical advice