Insulatard HM Injection (100IU/ml) – 3ml, 5 Penfills | Human Insulin (Isophane/NPH)

Description

Insulatard HM is a long-acting human insulin (NPH insulin/isophane insulin) that helps regulate blood sugar in people with diabetes mellitus (Type 1 and Type 2). It is supplied as Penfills for use with insulin pens, offering accurate dosing and convenience. Insulatard HM provides a steady, prolonged insulin release to maintain baseline glucose control throughout the day and night.

Ingredients

• Active Ingredient: Human Insulin (Isophane/NPH) 100 IU/ml

• Excipients: Zinc chloride, glycerol, phenol, protamine sulfate, water for injection

Drug Class

• Intermediate-acting Insulin (Antidiabetic Agent)

Dosage Form

• Injection (Suspension for subcutaneous use)

• Pre-filled 3ml Penfills, pack of 5

Uses / Indications

• Management of Type 1 Diabetes Mellitus

• Management of Type 2 Diabetes Mellitus (when oral therapy is inadequate)

• Blood sugar control during surgery, infections, or stressful conditions

Dosage

💉 Dose must be individualized by a physician based on blood sugar monitoring.

• Adults & Children: Varies depending on blood glucose level, diet, and activity

• Usual total daily insulin requirement: 0.5–1.0 IU/kg body weight (split doses if combined with short-acting insulin)

• Administer once or twice daily, usually in combination with a rapid- or short-acting insulin

In Case of Overdose

• Symptoms: Hypoglycemia (sweating, shakiness, confusion, headache, rapid heartbeat, fainting)

• Management: Immediate glucose administration (oral sugar, glucose tablets, or IV glucose in severe cases)

Missed Dose

• Take the next scheduled dose as prescribed

• Do not double dose to compensate

• Monitor blood glucose and inform physician if frequent doses are missed

How To Use

• Use only with a compatible insulin delivery pen

• Inject subcutaneously (thigh, upper arm, buttock, or abdomen)

• Rotate injection sites to avoid lipodystrophy (fat tissue changes)

• Do not inject intramuscularly or intravenously unless prescribed by a doctor

When Not to Use / Contraindications

• Hypersensitivity to human insulin or any excipient

• Hypoglycemia (low blood sugar at time of injection)

Side Effects

Common:

• Low blood sugar (hypoglycemia)

• Redness, swelling, or pain at injection site

• Mild weight gain

Serious (rare):

• Severe allergic reaction (rash, swelling, difficulty breathing)

• Lipodystrophy (skin thickening or pitting at injection site)

• Vision changes due to shifting glucose control

Precautions & Warnings

• Monitor blood glucose regularly

• Dose adjustments may be required during illness, stress, pregnancy, or surgery

• Use with caution in kidney or liver impairment

• Inform your doctor of all other medications

• Avoid alcohol (increases risk of hypoglycemia)

• Safe during pregnancy and breastfeeding but requires close medical supervision

Drug Interactions

• Hypoglycemia risk increased by: Oral antidiabetics, ACE inhibitors, beta-blockers, MAO inhibitors, sulfonamides, alcohol

• Reduced effect by: Corticosteroids, oral contraceptives, thyroid hormones, diuretics, sympathomimetics

Storage / Disposal

• Store in a refrigerator (2–8°C)

• Do not freeze

• Once in use, keep at room temperature (<25°C) for up to 4 weeks

• Keep away from direct heat and sunlight

• Dispose of used needles and penfills safely in a sharps container

Control Drug / Prescription Status

• Prescription-only medicine

Quick Tips

• Always check the insulin label before use to avoid mix-ups

• Roll the Penfill gently between hands before injection (suspension should look uniformly cloudy)

• Never share insulin pens or needles

• Carry a source of fast-acting sugar (glucose tablets or juice) in case of low blood sugar

• Regularly track HbA1c levels to ensure long-term glucose control