Description
Arynoin Plus (0.05% / 2%) Gel is a combination topical medication containing Tretinoin (0.05%) and Clindamycin (2%), used for the treatment of acne vulgaris, blackheads, whiteheads, and pimples.
It works by reducing inflammation, killing acne-causing bacteria, and unclogging pores to promote smoother, clearer skin.
This dual-action gel is designed to prevent new acne breakouts while healing existing ones.
Ingredients
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Active Ingredients: - 
Tretinoin 0.05% – A Vitamin A derivative that helps increase skin cell turnover and unclog pores. 
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Clindamycin 2% – An antibiotic that fights acne-causing bacteria and reduces inflammation. 
 
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Inactive Ingredients: - 
Carbomer 
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Propylene Glycol 
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Glycerin 
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Purified Water 
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Preservatives (as approved) 
 
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Drug Class
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Pharmacological Class: Retinoid & Antibiotic Combination 
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Therapeutic Class: Anti-acne / Dermatological 
Dosage Form
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Form: Topical Gel 
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Strength: Tretinoin 0.05% / Clindamycin 2% 
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Pack Size: 10g Tube 
Uses
Arynoin Plus Gel is indicated for the treatment of:
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Acne vulgaris (mild to moderate) 
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Inflamed pimples and pustules 
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Blackheads and whiteheads 
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Acne scars and post-acne marks 
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Oily skin and clogged pores 
Dosage
⚠️ Use as directed by your dermatologist.
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Apply once daily, preferably at night before bedtime. 
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Use a pea-sized amount for the entire face. 
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Avoid overuse, as it may increase irritation without improving results. 
In Case of Overdose
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Over-application may cause severe redness, peeling, or irritation. 
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If accidentally ingested, seek immediate medical help. 
Missed Dose
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Apply as soon as you remember. 
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If it’s close to the next scheduled time, skip the missed dose. 
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Do not double-apply to make up for a missed application. 
How To Use
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Wash your face with a gentle cleanser and pat dry. 
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Wait 10–15 minutes before applying the gel to completely dry skin. 
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Apply a thin layer evenly over the affected area. 
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Avoid contact with eyes, mouth, and mucous membranes. 
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Wash hands thoroughly after use. 
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Apply sunscreen during the day, as Tretinoin increases sun sensitivity. 
When Not to Use
Do not use Arynoin Plus Gel if you have:
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Allergy to Tretinoin, Clindamycin, or Lincomycin. 
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Eczema, sunburn, or broken skin. 
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History of regional enteritis or ulcerative colitis (for Clindamycin). 
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Pregnancy or breastfeeding, unless prescribed by your doctor. 
Side Effects
Common:
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Mild redness or burning sensation 
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Peeling or dryness of skin 
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Temporary worsening of acne (initially) 
Uncommon:
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Skin itching or irritation 
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Increased sun sensitivity 
Rare but Serious:
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Allergic reaction (rash, swelling, severe irritation) 
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Diarrhea or stomach cramps (from systemic absorption of Clindamycin) 
Precautions & Warnings
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For external use only. 
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Avoid excessive sun exposure; use broad-spectrum sunscreen daily. 
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Avoid harsh soaps, scrubs, or astringents while using this gel. 
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Do not use with other retinoids, benzoyl peroxide, or strong acne treatments without doctor’s advice. 
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Discontinue if severe irritation, peeling, or rash occurs. 
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Keep out of reach of children. 
Drug Interactions
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Avoid using with other topical retinoids, keratolytics, or alcohol-based products. 
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Do not use with Erythromycin-containing products (may cause antagonistic effect). 
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Inform your doctor about all topical or oral acne medications you are using. 
Storage/Disposal
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Store below 25°C in a cool, dry place. 
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Keep away from direct sunlight and heat. 
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Do not freeze. 
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Close the tube tightly after each use. 
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Dispose of properly after expiration date. 
Control Drug
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Prescription-only medicine (Rx) 
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Not a controlled substance 
Quick Tips
💡 Helpful Advice:
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Apply only at night and wash off in the morning. 
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Always moisturize to reduce dryness and irritation. 
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Avoid waxing, laser, or chemical peels during treatment. 
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Visible results usually appear after 4–8 weeks of consistent use. 
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Consult your dermatologist before using with other acne medications. 
 
  
  
 
                
 
   
                   
                   
                    
                   
         
   
         
   
         
   
         
   
         
   
         
  
 
   
   
   
   
       
     
       
     
       
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