Diagesic Extra Tablets 325mg/37.5mg – Pain Relief with Paracetamol & Tramadol (10’s)

Description:

Diagesic Extra 325/37.5mg Tablets combine Tramadol Hydrochloride (37.5 mg) and Paracetamol (325 mg) to provide effective pain relief for moderate to severe pain that cannot be controlled by over-the-counter medicines alone.

This dual-action formula works by blocking pain signals in the brain and spinal cord and reducing inflammation and fever, offering both fast and lasting relief for conditions like back pain, arthritis, injury, and post-surgical pain.

Each pack contains 10 tablets, ideal for short-term pain management under medical supervision.

Ingredients:

Each tablet contains:

• Tramadol Hydrochloride – 37.5 mg

• Paracetamol (Acetaminophen) – 325 mg

Inactive ingredients: Microcrystalline cellulose, maize starch, povidone, magnesium stearate, and other standard excipients.

Drug Class:

• Opioid Analgesic Combination
  (Tramadol – centrally acting opioid analgesic; Paracetamol – non-opioid analgesic/antipyretic)

Dosage Form:

• Film-coated Tablet

Uses:

Diagesic Extra is used for the relief of moderate to moderately severe pain, including:

• Musculoskeletal pain (backache, neck pain)

• Arthritis and joint pain

• Post-operative pain

• Dental pain

• Injury-related pain

• Menstrual cramps

Dosage:

• Adults and adolescents (12 years and above):
  1–2 tablets every 4–6 hours as needed.
  Maximum dose: 8 tablets in 24 hours.

⚠️ Do not exceed the recommended dose or use for more than 5 days without medical advice.

In Case of Overdose:

Overdose symptoms may include:

• Nausea, vomiting, sweating

• Drowsiness or confusion

• Liver damage (from Paracetamol)

• Slow breathing or unconsciousness (from Tramadol)

👉 Seek immediate emergency medical help if overdose is suspected.

Missed Dose:

• If you miss a dose, take it as soon as you remember.

• If it’s almost time for the next dose, skip the missed one.

• Do not double dose to make up for a missed tablet.

How To Use:

1. Take orally with a full glass of water.

2. May be taken with or without food, but food may reduce stomach upset.

3. Follow your doctor’s prescribed schedule strictly.

4. Do not crush or chew the tablet.

When Not to Use:

Do not use Diagesic Extra if you:

• Are allergic to Tramadol, Paracetamol, or any excipient.

• Have severe liver or kidney disease.

• Suffer from severe asthma or breathing problems.

• Have recently used alcohol, sedatives, or opioids.

• Are taking MAO inhibitors (used for depression) or have used them within the last 14 days.

• Have a history of drug or alcohol abuse.

Side Effects:

Common:

• Drowsiness or dizziness

• Nausea or vomiting

• Headache

• Constipation

• Dry mouth

• Sweating

Serious (seek medical help):

• Slow or shallow breathing

• Severe abdominal pain or yellowing of skin (liver damage)

• Seizures

• Allergic reactions (rash, swelling, difficulty breathing)

Precautions & Warnings:

• Use only under medical supervision.

• Avoid alcohol or other sedatives – may increase drowsiness or breathing risk.

• Not suitable for children under 12 years.

• Elderly patients may be more sensitive to side effects.

• Pregnant or breastfeeding women should avoid unless prescribed by a doctor.

• Long-term use may lead to dependence or withdrawal symptoms.

Drug Interactions:

May interact with:

• CNS depressants (alcohol, sleeping pills, tranquilizers)

• MAO inhibitors or SSRIs (risk of serotonin syndrome)

• Carbamazepine or rifampicin (reduces Tramadol effect)

• Warfarin (may increase bleeding risk)

• Other Paracetamol-containing drugs (increases risk of liver damage)

👉 Always tell your doctor about all medications and supplements you’re taking.

Storage/Disposal:

• Store below 30°C, away from light and moisture.

• Keep out of reach of children.

• Do not use after expiry date.

• Dispose of unused tablets safely as per pharmacist’s instructions.

Control Drug:

• Prescription-Only Medicine (Rx)

• Controlled Substance due to Tramadol content.

Quick Tips:

• Avoid driving or operating machinery until you know how the medicine affects you.

• Do not drink alcohol while taking Diagesic Extra.

• Take exactly as prescribed – misuse can cause dependence.

• If pain persists beyond a few days, consult your doctor.

• Drink plenty of water and maintain a healthy diet to avoid constipation.