Astadol 37.5mg/325mg Tablets (20’s) – Dual Action Pain Relief for Moderate to Severe Pain

Description

Astadol 37.5/325mg Tablets is a combination pain-relief medication that contains Tramadol Hydrochloride (37.5 mg) and Paracetamol (325 mg). This formulation provides fast and long-lasting relief from moderate to severe pain by combining two effective analgesics with complementary actions.

Tramadol works by blocking pain signals in the brain, while Paracetamol reduces pain and fever. Together, they help manage conditions such as postoperative pain, musculoskeletal pain, arthritis, and nerve pain.

Ingredients

Each tablet contains:

• Tramadol Hydrochloride BP – 37.5 mg

• Paracetamol BP – 325 mg

Inactive Ingredients: Microcrystalline cellulose, starch, povidone, magnesium stearate, and purified water.

Drug Class

• Analgesic (Pain Reliever)

• Opioid and Non-Opioid Combination

Dosage Form

Tablet

Uses

Astadol Tablets are used for the relief of:

• Moderate to severe pain

• Post-surgical pain

• Arthritis and osteoarthritis pain

• Lower back pain

• Dental pain

• Nerve-related (neuropathic) pain

• Musculoskeletal injuries and trauma

Dosage

• Adults: 1–2 tablets every 4 to 6 hours as needed for pain relief.

• Maximum daily dose: 8 tablets (equivalent to 300 mg Tramadol and 2600 mg Paracetamol) in 24 hours.

• Elderly or patients with kidney/liver impairment: Use lower doses under medical supervision.

💊 Always take the lowest effective dose for the shortest duration possible.

In Case of Overdose

Symptoms may include:

• Nausea, vomiting, abdominal pain, confusion, drowsiness, slow breathing, or liver damage.

Action:

• Seek immediate medical help.

• Treatment includes supportive care, and activated charcoal or antidotes (Naloxone for Tramadol toxicity, N-acetylcysteine for Paracetamol overdose) may be administered in a hospital setting.

Missed Dose

• Take as soon as you remember if needed for pain.

• If it’s close to your next dose, skip the missed one.

• Do not double doses to compensate.

How To Use

1. Take with a full glass of water, with or without food.

2. Do not crush or chew the tablet.

3. Follow your doctor’s prescription carefully.

4. Avoid using for longer than prescribed to prevent dependence.

When Not to Use

❌ Known allergy to Tramadol or Paracetamol.
❌ Severe liver or kidney disease.
❌ Patients with respiratory depression or asthma attacks.
❌ Concurrent use with alcohol, sedatives, or other opioid painkillers.
❌ Children under 12 years of age or post-tonsillectomy patients under 18.
❌ Pregnancy or breastfeeding, unless directed by a doctor.

Side Effects

Common:

• Dizziness, nausea, constipation, dry mouth, sweating, or drowsiness.

• Headache or mild stomach upset.

Less Common:

• Fatigue, insomnia, blurred vision, itching, or tremors.

Serious (Seek medical help immediately):

• Slow or shallow breathing

• Seizures or loss of consciousness

• Severe skin rash

• Yellowing of skin or eyes (liver issues)

Precautions & Warnings

⚠️ Use with caution in:

• Elderly or debilitated patients

• Liver or kidney disease

• Epilepsy (risk of seizures)

• Alcohol or drug dependence history

⚠️ Avoid driving or operating heavy machinery — may cause drowsiness or dizziness.
⚠️ Prolonged use can lead to tolerance or dependence — use only under medical advice.

Drug Interactions

Do not use Astadol with:

• Alcohol – increases risk of liver damage and sedation.

• Benzodiazepines, sedatives, or sleeping pills – increases drowsiness and respiratory depression.

• MAO inhibitors or SSRIs – may cause serotonin syndrome.

• Warfarin – may increase bleeding risk.

• Other Tramadol or Paracetamol products – risk of overdose.

Storage/Disposal

• Store below 30°C, in a cool, dry place away from sunlight.

• Keep out of reach of children.

• Do not use beyond expiry date.

• Dispose of properly; do not flush or throw into household waste.

Control Drug

✅ Prescription Required
⚠️ Controlled Drug (Schedule IV in some regions) – due to the Tramadol component.

Quick Tips

💡 Take only when needed — not for long-term continuous use.
💡 Avoid alcohol and sedatives during treatment.
💡 Drink plenty of water and eat fiber-rich foods to prevent constipation.
💡 Report any unusual mood changes, drowsiness, or breathing problems.
💡 Keep track of doses — do not exceed the daily limit.

✅ Pack Size: 20 Tablets
✅ Active Ingredients: Tramadol Hydrochloride 37.5 mg + Paracetamol 325 mg
✅ Manufacturer: [Insert Manufacturer Name]
✅ Category: Pain Relief / Analgesics