Description:
Savesto 50 (24/26mg) is a combination medication containing Sitagliptin 24mg and Metformin 26mg (extended release formulation). It is used to manage type 2 diabetes by controlling blood sugar levels. Sitagliptin increases insulin release and decreases glucagon levels, while Metformin improves insulin sensitivity and reduces glucose production in the liver. Together, they provide effective glycemic control.
Ingredients:
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Active Ingredients:
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Sitagliptin 24mg
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Metformin 26mg (extended release)
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Inactive Ingredients: Microcrystalline cellulose, croscarmellose sodium, magnesium stearate, povidone, hydroxypropyl methylcellulose, titanium dioxide (coating), lactose monohydrate
Drug Class:
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Combination therapy: DPP-4 inhibitor + Biguanide (oral antidiabetic)
Dosage Form:
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Extended-release film-coated tablets
Uses:
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Controls blood sugar in type 2 diabetes
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Reduces HbA1c levels
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Improves insulin sensitivity
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Supports overall diabetes management
Dosage:
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Typically 1 tablet once or twice daily, with meals, as prescribed by a doctor
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Dose may be adjusted based on blood sugar levels and kidney function
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Follow doctor’s instructions carefully
In Case of Overdose:
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Seek immediate medical attention. Symptoms may include severe hypoglycemia, nausea, vomiting, dizziness, or lactic acidosis (rare)
Missed Dose:
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Take as soon as remembered unless it is near the next scheduled dose. Do not double the dose
How To Use:
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Swallow the tablet whole with water
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Take with meals to reduce gastrointestinal side effects
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Do not crush or chew extended-release tablets
When Not to Use:
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Allergy to Sitagliptin, Metformin, or other ingredients
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Severe kidney or liver disease
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Diabetic ketoacidosis or type 1 diabetes
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Pregnancy or breastfeeding without doctor’s advice
Side Effects:
Common:
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Nausea or vomiting
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Diarrhea
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Stomach discomfort
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Mild headache
Serious (seek medical attention):
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Lactic acidosis (rare but serious: muscle pain, weakness, breathing difficulty)
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Severe hypoglycemia (especially if combined with other antidiabetic medications)
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Allergic reactions such as rash, swelling, or difficulty breathing
Precautions & Warnings:
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Regular monitoring of blood sugar, kidney, and liver function is recommended
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Maintain adequate hydration
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Inform your doctor about all medications and medical conditions
Drug Interactions:
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May interact with insulin, sulfonylureas, and other antidiabetic medications
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Avoid unnecessary combination with other DPP-4 inhibitors or Metformin-containing products
Storage/Disposal:
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Store at room temperature, away from moisture and sunlight
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Keep out of reach of children
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Dispose of properly; do not flush
Control Drug:
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Prescription-only medication
Quick Tips:
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Take at the same time daily for consistent blood sugar control
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Take with meals to reduce stomach upset
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Maintain a balanced diet and regular exercise
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Monitor for side effects and consult your doctor if needed



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