Humalog Mix-50 (100IU/ml) – 3ml, 5 Cartridges | Insulin for Diabetes Management

Description

Humalog Mix-50 (100IU/ml) is a premixed insulin formulation containing 50% insulin lispro solution (rapid-acting) and 50% insulin lispro protamine suspension (intermediate-acting). It is used to control high blood sugar in patients with diabetes mellitus. This insulin combination works quickly to lower blood glucose after meals and also provides longer coverage to maintain stable sugar levels throughout the day.

Ingredients

• Active Ingredients:

  • Insulin Lispro (50%) – rapid-acting

  • Insulin Lispro Protamine (50%) – intermediate-acting

• Inactive Ingredients: Zinc, m-cresol, glycerin, dibasic sodium phosphate, water for injection.

Drug Class

Antidiabetic – Insulin (Premixed Insulin Analog)

Dosage Form

Injection – 3ml Cartridges (Pack of 5)

Uses

• Management of Type 1 Diabetes Mellitus

• Management of Type 2 Diabetes Mellitus (when oral medicines are not sufficient)

• Helps in controlling post-meal blood sugar spikes

• Provides 24-hour coverage when used with proper diet and exercise

Dosage

• Dosage is individualized by the healthcare provider depending on blood sugar levels, diet, and response.

• Typically injected subcutaneously before meals.

• Rotation of injection sites is necessary to avoid lipodystrophy.

• Do not self-adjust dose without consulting a doctor.

In case of Overdose

• Symptoms: Severe hypoglycemia, sweating, shakiness, dizziness, rapid heartbeat, seizures, or loss of consciousness.

• Immediate intake of glucose or IV dextrose (in hospital setting) is required.

Missed Dose

• Take the missed dose as soon as you remember if it is close to mealtime.

• If the next dose is near, skip the missed one.

• Do not double the dose.

How To Use

• Use only with compatible insulin pens that accept 3ml cartridges.

• Insert cartridge correctly into the pen device.

• Administer subcutaneously (under the skin) in areas like abdomen, thigh, or upper arm.

• Never inject intravenously.

• Monitor blood sugar levels regularly.

When Not to Use

• Patients allergic to insulin lispro or formulation components

• During episodes of hypoglycemia (low blood sugar)

• Without a doctor’s prescription and supervision

Side Effects

Common:

• Hypoglycemia (low blood sugar)

• Redness, pain, or swelling at injection site

• Headache, dizziness, sweating

Rare but Serious:

• Severe allergic reactions (anaphylaxis)

• Vision changes

• Lipodystrophy (fat tissue changes at injection site)

Precautions & Warnings

• Regularly monitor blood sugar and HbA1c.

• Use cautiously in patients with renal or hepatic impairment.

• Dose adjustments may be needed during illness, stress, or surgery.

• Consult doctor before use if pregnant or breastfeeding.

• Do not skip meals after taking Humalog Mix-50.

Drug Interactions

May interact with:

• Oral antidiabetics (e.g., metformin, sulfonylureas)

• Beta-blockers (may mask hypoglycemia symptoms)

• Corticosteroids (increase blood sugar)

• Diuretics and thyroid hormones (affect insulin requirements)

Storage/Disposal

• Store unopened cartridges in a refrigerator (2–8°C).

• Do not freeze.

• Once in use, keep at room temperature (below 30°C) and use within 28 days.

• Protect from direct sunlight and heat.

• Dispose of used needles safely in a sharps container.

Control Drug

Prescription-only medicine (not a controlled substance).

Quick Tips

• Always carry a source of glucose (sugar candy/juice) in case of hypoglycemia.

• Maintain a proper diet and exercise routine along with insulin therapy.

• Rotate injection sites to prevent skin complications.

• Keep spare cartridges and pens handy when traveling.

• Never stop insulin suddenly without consulting your doctor.