Oxidil 250mg IV Injection | Broad-Spectrum Antibiotic for Bacterial Infections

Description

Oxidil (250mg) IV Injection is a broad-spectrum antibiotic containing cefotaxime, a third-generation cephalosporin. It is widely used in hospitals to treat moderate to severe bacterial infections caused by susceptible organisms. Administered via intravenous injection, it helps combat infections of the respiratory tract, urinary tract, skin, soft tissues, bones, joints, abdomen, and the central nervous system.

Ingredients

• Active Ingredient: Cefotaxime Sodium (250mg)

• Inactive Ingredients: Sterile excipients and diluents for IV administration

Drug Class

Antibiotic – Cephalosporin (3rd Generation)

Dosage Form

• Intravenous (IV) Injection

• 250mg per vial

Uses

Oxidil is prescribed for the treatment of:

• Respiratory tract infections (pneumonia, bronchitis)

• Urinary tract infections (UTIs)

• Skin and soft tissue infections

• Bone and joint infections

• Abdominal infections (peritonitis)

• Meningitis and other central nervous system infections

• Septicemia and bloodstream infections

• Post-surgical infections

Dosage

• Adults: Typically 1–2g every 8–12 hours, depending on infection severity.

• Children: Dose adjusted according to body weight and infection type.

• Must be administered by a healthcare professional.

• Always follow your doctor’s prescription; do not self-administer.

In case of Overdose

Symptoms may include seizures, confusion, nausea, and gastrointestinal upset. Immediate medical attention is required. Supportive treatment should be initiated in a hospital setting.

Missed Dose

Since Oxidil is given in a hospital or under professional supervision, a missed dose is unlikely. If missed, it should be administered as soon as possible under medical guidance.

How To Use

• Reconstitute the powder with the recommended sterile solution before administration.

• Administer intravenously by a qualified healthcare professional.

• Complete the full prescribed course even if symptoms improve early.

When Not to Use

• Allergy to cefotaxime, cephalosporins, or penicillin derivatives.

• Patients with severe history of hypersensitivity reactions to beta-lactam antibiotics.

Side Effects

Common:

• Pain or swelling at injection site

• Nausea, vomiting, diarrhea

• Headache

Rare but Serious:

• Severe allergic reactions (rash, itching, difficulty breathing, swelling)

• Clostridium difficile–associated diarrhea

• Blood disorders (anemia, low platelets, leukopenia)

• Seizures (especially in renal impairment or overdose)

Precautions & Warnings

• Inform doctor about any allergies to penicillin/cephalosporins.

• Use with caution in patients with kidney or liver impairment.

• Prolonged use may lead to superinfections (fungal/secondary bacterial).

• Safe use in pregnancy and lactation should be confirmed by a doctor.

Drug Interactions

Oxidil may interact with:

• Aminoglycosides (increased risk of kidney toxicity)

• Loop diuretics (e.g., furosemide)

• Anticoagulants (e.g., warfarin – may enhance bleeding risk)

• Probenecid (may increase cefotaxime levels in blood)

Storage/Disposal

• Store vials at room temperature (below 25°C) in a dry place.

• Protect from direct sunlight and moisture.

• Once reconstituted, use immediately or as per hospital protocol.

• Dispose of needles and vials safely in accordance with biomedical waste guidelines.

Control Drug

Not a controlled drug, but prescription required.

Quick Tips

• Always complete the full antibiotic course to prevent resistance.

• Inform your doctor if you experience severe diarrhea, as it may indicate colitis.

• Keep track of any allergies before starting treatment.

• Do not share medication with others.