Tonoflex Injection (100mg/2ml) – 5 Ampoules

Description

Tonoflex Injection contains Ketoprofen (100mg/2ml), a non-steroidal anti-inflammatory drug (NSAID). It is widely used to relieve pain, inflammation, and swelling associated with conditions like arthritis, muscle pain, joint pain, trauma, and post-surgical pain. Tonoflex provides quick relief when oral painkillers are not effective or cannot be taken.

Ingredients

• Active Ingredient: Ketoprofen 100mg/2ml

• Inactive Ingredients: Water for injection and stabilizers (may vary by manufacturer)

Drug Class

Non-Steroidal Anti-Inflammatory Drug (NSAID)

Dosage Form

Injection (Intramuscular or Intravenous) – 2ml ampoules

Uses

• Relief of moderate to severe pain (musculoskeletal, joint, back pain)

• Management of osteoarthritis and rheumatoid arthritis flare-ups

• Pain relief in post-operative and post-traumatic conditions

• Pain due to toothache, fractures, sprains, or strains

Dosage

• Adults: 100mg (1 ampoule) once or twice daily, depending on severity

• Administered intramuscularly (IM) or intravenously (IV) under medical supervision

• Do not exceed 200mg per day unless prescribed by a doctor

In Case of Overdose

• Symptoms: Nausea, vomiting, stomach pain, drowsiness, dizziness, difficulty breathing, bleeding, seizures

• Management: Immediate medical attention, gastric lavage, activated charcoal, and supportive treatment

Missed Dose

• If a dose is missed, take it as soon as possible

• If it’s nearly time for the next dose, skip the missed one

• Do not double dose

How to Use

• Administered by a healthcare professional only

• Injected intramuscularly deep into the muscle or slow IV infusion

• Never self-inject without medical guidance

When Not to Use

• Allergy to Ketoprofen, aspirin, or other NSAIDs

• History of asthma, peptic ulcers, or GI bleeding

• Patients with severe kidney, liver, or heart disease

• During pregnancy (3rd trimester) and breastfeeding unless prescribed

• Patients with bleeding disorders

Side Effects

Common:

• Pain, redness, or swelling at injection site

• Nausea, vomiting, diarrhea

• Indigestion, abdominal pain

• Dizziness, drowsiness

Serious (seek medical help):

• Stomach/intestinal bleeding (black stools, vomiting blood)

• Severe allergic reaction (rash, breathing difficulty, swelling)

• Liver/kidney function changes

• Chest pain or shortness of breath

Precautions & Warnings

• Use with caution in elderly patients (higher risk of GI bleeding)

• Avoid alcohol (increases stomach bleeding risk)

• Monitor blood pressure during long-term use

• Not recommended for long-term use without medical advice

• Inform doctor about any history of ulcers, asthma, or heart disease

Drug Interactions

• Other NSAIDs (ibuprofen, diclofenac, aspirin) – increase risk of bleeding

• Anticoagulants (warfarin, heparin) – higher bleeding risk

• Corticosteroids – increased stomach irritation/ulcer risk

• Diuretics and antihypertensives – reduced effect

• Lithium, methotrexate – increased toxicity

Storage/Disposal

• Store below 25°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

• Dispose of used ampoules safely in sharps containers

Control Drug

• No – Not a controlled drug (Prescription required)

Quick Tips

• Do not use for more than a few days without medical advice

• Take food or milk with NSAIDs (if oral form is prescribed) to protect stomach

• Report any stomach pain, black stools, or vomiting blood immediately

• Avoid alcohol and smoking (increase GI bleeding risk)

• Use only as prescribed by your doctor