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Cytotrexate (2.5mg) contains Methotrexate, an immunosuppressant and anti-inflammatory medication used to treat various conditions such as rheumatoid arthritis, psoriasis, and certain types of cancer.
It works by inhibiting the metabolism of folic acid, which reduces the growth of rapidly dividing cells, including immune cells that contribute to inflammation and autoimmune responses.
Cytotrexate helps reduce inflammation, slow disease progression, and manage symptoms of autoimmune and inflammatory disorders.
Active Ingredient:
Methotrexate 2.5mg
Inactive Ingredients: Microcrystalline cellulose, lactose, starch, magnesium stearate, and other excipients
Antimetabolite / Immunosuppressant
Oral Tablet
Cytotrexate 2.5mg is used for:
Rheumatoid arthritis and other autoimmune disorders
Severe psoriasis
Certain types of cancer (e.g., leukemia, lymphoma)
Management of inflammation and immune system overactivity
Adults: Usually one or more tablets weekly, as prescribed by your doctor.
Dosage varies based on the condition being treated, body weight, and response.
Strictly follow your doctor’s schedule to avoid serious side effects.
Overdose may cause:
Nausea, vomiting, or diarrhea
Mouth sores or ulcers
Low blood counts (anemia, infections, bleeding)
Liver or kidney damage
Seek immediate medical attention.
Take the missed dose as soon as you remember if it is close to your scheduled day.
Do not double the dose to compensate.
Contact your doctor for guidance if unsure.
Take orally with water
Can be taken with or without food
Follow your doctor’s exact dosing schedule (usually weekly)
Regular monitoring of blood counts and liver/kidney function is required
Do not use Cytotrexate if you have:
Severe liver or kidney disease
Blood disorders or low blood counts
Pregnancy or breastfeeding (can harm fetus or infant)
Known hypersensitivity to Methotrexate
Active infections
Common:
Nausea, vomiting, or loss of appetite
Mouth sores or ulcers
Fatigue or mild hair thinning
Serious (seek immediate medical attention):
Severe infections due to low immunity
Unusual bleeding or bruising
Liver toxicity (yellowing of skin/eyes)
Lung problems (cough, shortness of breath)
Regular blood tests for liver, kidney, and blood cell counts are essential
Avoid alcohol to reduce liver toxicity
Use effective contraception during treatment and for several months after
Inform your doctor about all other medications, supplements, or herbal remedies
Cytotrexate may interact with:
NSAIDs (e.g., ibuprofen)
Antibiotics (e.g., trimethoprim, penicillin)
Other immunosuppressants or chemotherapy drugs
Folic acid supplements (may need adjustment)
Store in a cool, dry place below 30°C
Protect from moisture and light
Keep out of reach of children
Dispose of properly; do not flush down drains or toilets
Prescription-Only Medicine
Take exactly as prescribed by your doctor (weekly, not daily)
Attend all monitoring appointments for blood and liver tests
Avoid infections by practicing good hygiene
Report any unusual bruising, bleeding, or persistent cough
Limit alcohol consumption
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