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DioPlus (5/160mg) is a combination medication containing Losartan (5mg) and Hydrochlorothiazide (160mg).
It is primarily used to manage high blood pressure (hypertension) and reduce the risk of heart attack, stroke, and kidney complications. Losartan works by relaxing blood vessels, while Hydrochlorothiazide acts as a diuretic, helping the body remove excess salt and water.
Active Ingredients:
Losartan Potassium 5mg
Hydrochlorothiazide 160mg
Inactive Ingredients: Microcrystalline cellulose, lactose, magnesium stearate, starch, and other excipients
Antihypertensive Combination (ARB + Thiazide Diuretic)
Oral Tablet
DioPlus 5/160mg is used for:
High blood pressure (hypertension)
Reducing the risk of stroke and heart attack
Managing fluid retention (edema)
Protecting kidneys in patients with hypertension
Adults: Usually 1 tablet once daily, or as prescribed by your doctor
Take at the same time each day for consistent blood pressure control
Do not adjust the dose without consulting your physician
Overdose may cause:
Severe dizziness or fainting
Low blood pressure
Irregular heartbeat or dehydration
Seek immediate medical attention.
Take the missed dose as soon as you remember.
If it is almost time for the next dose, skip the missed dose.
Do not double the dose.
Take orally with or without food
Swallow the tablet whole with a full glass of water
Monitor blood pressure regularly for effectiveness
Do not use DioPlus if you have:
Severe kidney or liver problems
Low potassium or sodium levels
Allergy to Losartan, Hydrochlorothiazide, or other sulfonamides
Pregnancy or breastfeeding (consult doctor first)
Common:
Dizziness or lightheadedness
Headache
Increased urination
Serious (seek immediate medical attention):
Swelling of face, lips, or throat (allergic reaction)
Irregular heartbeat
Severe dehydration or electrolyte imbalance
Monitor kidney function and electrolytes regularly
Avoid sudden position changes to prevent dizziness
Limit potassium supplements unless prescribed
Inform your doctor about all other medications, including NSAIDs
DioPlus may interact with:
Other blood pressure medications
Potassium supplements or salt substitutes
NSAIDs (e.g., ibuprofen, naproxen)
Lithium or certain diabetes medications
Store in a cool, dry place below 25°C
Protect from moisture and sunlight
Keep out of reach of children
Dispose of properly; do not flush down drains or toilets
Prescription-Only Medicine
Take at the same time each day for optimal blood pressure control
Drink adequate fluids unless otherwise directed by your doctor
Monitor blood pressure and report significant changes
Avoid alcohol which may enhance dizziness or low blood pressure
Follow dietary advice regarding salt and potassium intake
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