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Tramal SR 100mg Tablets contain Tramadol Hydrochloride (sustained-release), an opioid analgesic and serotonin-norepinephrine reuptake inhibitor (SNRI). It is designed for long-lasting relief of moderate to severe pain, including chronic musculoskeletal pain, osteoarthritis, rheumatoid arthritis, and postoperative or injury-related pain.
Tramal SR works by acting on the central nervous system to change the perception of pain and improve patient comfort over a sustained period. Its extended-release formulation allows twice-daily dosing while maintaining stable blood levels.
Active Ingredient: Tramadol Hydrochloride 100mg (sustained-release) per tablet
Inactive Ingredients: Standard excipients (fillers, binders, coatings—details on packaging)
Opioid Analgesic
Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Oral tablet (extended-release)
Strength: 100mg
Pack Size: 10 tablets
Tramal SR 100mg Tablets are indicated for:
Relief of moderate to severe chronic pain
Pain associated with osteoarthritis and rheumatoid arthritis
Postoperative pain management
Injury-related pain and musculoskeletal disorders
Other chronic pain conditions requiring long-lasting analgesia
Typical Adult Dose: 100mg orally every 12 hours
Maximum Dose: 300mg per day
Administration: Swallow whole; do not crush, chew, or break the tablet to avoid rapid release and overdose
Individualization: Dose may be adjusted based on pain severity, patient response, and tolerability
Symptoms: Extreme drowsiness, slowed or difficult breathing, low blood pressure, coma
Action: Seek immediate medical attention. Bring the medication packaging and prescription details to the hospital
Take the missed dose as soon as you remember unless it is almost time for the next scheduled dose
Do not double the next dose to make up for a missed one
Take Tramal SR exactly as prescribed
Swallow the tablet whole with water
Can be taken with or without food, but maintain consistency
Do not stop abruptly; tapering may be required to avoid withdrawal symptoms
Allergy to Tramadol or tablet excipients
Severe liver or kidney impairment
History of seizures or significant CNS disorders
Concurrent use with alcohol or other CNS depressants
Children under 12 years or post-tonsil/adenoid surgery in children under 18
Common:
Drowsiness, dizziness
Nausea, vomiting
Constipation
Sweating
Dry mouth
Serious:
Seizures
Serotonin syndrome (agitation, hallucinations, fever, rapid heart rate, muscle stiffness)
Slow or difficult breathing
Severe allergic reactions (rash, swelling, difficulty breathing)
Avoid alcohol and CNS depressants
Exercise caution while driving or operating machinery
Monitor for serotonin syndrome when used with other serotonergic drugs
Use with caution in patients with a history of seizures or substance abuse
Gradual tapering may be necessary when discontinuing
CNS depressants (sedatives, alcohol) increase drowsiness risk
SSRIs, SNRIs, MAOIs, or other serotonergic drugs may increase the risk of serotonin syndrome
CYP2D6 inhibitors (like fluoxetine, quinidine) may affect tramadol metabolism
Store at room temperature, away from moisture and heat
Keep out of reach of children
Dispose of unused tablets safely; do not flush down the toilet
Prescription-only medication
Use only under supervision of a qualified healthcare provider
Take at the same time each day to maintain consistent pain control
Monitor for drowsiness or dizziness, especially during initial doses
Inform doctors and dentists of your use of Tramal SR before procedures
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