HY-Cortisone 250mg Injection (Hydrocortisone Sodium Succinate) – Corticosteroid for Severe Inflammation & Adrenal Crisis

Description

HY-Cortisone 250mg Injection contains Hydrocortisone Sodium Succinate, a corticosteroid medication widely used for treating severe allergic reactions, inflammation, adrenal insufficiency (Addison’s disease, adrenal crisis), and life-threatening conditions such as shock due to infections or trauma.

It works by reducing inflammation and suppressing the immune system, making it a life-saving treatment in emergencies. This medicine is usually given in a hospital setting by a doctor or nurse through intravenous (IV) or intramuscular (IM) injection.

Ingredients

• Active Ingredient: Hydrocortisone Sodium Succinate (250mg)

• Inactive Ingredients: Buffers and sterile water for injection

Drug Class

• Corticosteroid / Glucocorticoid

Dosage Form

• Injection (Vial / Ampoule, 250mg)

Uses

HY-Cortisone 250mg Injection is prescribed for:

• Adrenal insufficiency & adrenal crisis

• Severe allergic reactions (anaphylaxis)

• Acute asthma attacks & COPD flare-ups

• Rheumatic disorders (arthritis, lupus)

• Endocrine disorders requiring steroid replacement

• Life-threatening shock (due to sepsis, trauma, surgery)

• Severe skin & autoimmune conditions

• Organ transplant & immune suppression

Dosage

• Adults:

  • Initial emergency dose: 100–500mg IV injection depending on condition.

  • Maintenance: 250mg every 4–6 hours as directed by doctor.

• Children:

  • Doses are weight-based (usually 0.56–8mg/kg/day).

• Always follow doctor’s prescription.

In Case of Overdose

• Symptoms: Mood changes, confusion, high blood pressure, high blood sugar, electrolyte imbalance.

• Action: Seek immediate medical help. Supportive treatment required.

Missed Dose

• Usually hospital-administered, so missed doses are rare.

• If self-administering at home, take as soon as possible, but do not double dose.

How To Use

• Administered by IV or IM injection under medical supervision.

• Not for self-use unless trained and prescribed by doctor.

• Follow recommended dosing strictly.

When Not to Use

Do not use HY-Cortisone if:

• You are allergic to hydrocortisone or other corticosteroids

• You have systemic fungal infections (unless doctor permits)

• You are taking live vaccines during high-dose steroid therapy

• You have untreated infections without antibiotics

Side Effects

Common:

• Pain at injection site

• Increased appetite & weight gain

• Stomach upset, bloating

• Mood swings, irritability

Serious:

• High blood pressure, high blood sugar

• Vision problems (glaucoma, cataracts)

• Muscle weakness, osteoporosis

• Swelling of face/feet (fluid retention)

• Increased risk of infections

Precautions & Warnings

• Use with caution in diabetes, hypertension, heart disease, or osteoporosis.

• Long-term use must be tapered gradually to prevent adrenal crisis.

• Avoid contact with people having infections like chickenpox or measles.

• Pregnant or breastfeeding women should consult their doctor before use.

Drug Interactions

• NSAIDs (ibuprofen, aspirin – ↑ risk of ulcers)

• Diuretics (↑ risk of low potassium)

• Antidiabetic drugs (reduced effect)

• Live vaccines (risk of infection)

• Antifungals (ketoconazole ↑ steroid effect)

• Anticonvulsants (phenytoin, carbamazepine ↓ steroid effect)

Storage/Disposal

• Store below 25°C, away from sunlight.

• Do not freeze.

• Keep away from children.

• Dispose of unused ampoules/vials safely as per pharmacist’s advice.

Control Drug

• Not a controlled substance

• Prescription-only medicine (Rx)

Quick Tips

• Do not stop HY-Cortisone suddenly; taper gradually with doctor’s advice.

• Carry a steroid card/ID if you are on long-term therapy.

• Eat calcium & vitamin D-rich foods to protect bones.

• Monitor blood pressure, sugar, and weight during therapy.

• Inform your doctor before any surgery or vaccination.