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Orno (8mg/2ml) Injection contains Ondansetron, a powerful antiemetic used to prevent and treat nausea and vomiting. It is commonly given to patients undergoing chemotherapy, radiotherapy, or surgery. The medicine works by blocking serotonin (5-HT3) receptors in the brain and gut, which trigger nausea and vomiting reflexes.
Active Ingredient: Ondansetron (8mg/2ml)
Inactive Ingredients: Sodium chloride, water for injection, and stabilizers
Antiemetic
Selective 5-HT3 Receptor Antagonist
Injection (2ml vial)
Prevention of chemotherapy-induced nausea and vomiting
Prevention of nausea and vomiting after radiotherapy
Management of post-operative nausea and vomiting
Sometimes used in other severe nausea cases when oral therapy is not possible
Adults (Chemotherapy): 8mg IV/IM just before treatment, followed by additional doses as prescribed.
Post-operative nausea: 4mg IV administered before or after surgery.
Pediatric use: dose adjusted according to body weight and doctor’s instructions.
⚠️ Dosage must always be determined by a doctor.
Symptoms: Vision disturbances, constipation, severe hypotension, fainting.
Emergency medical care required immediately.
If missed during hospital treatment, the healthcare provider will reschedule.
Do not take a double dose.
Administered intravenously (IV) or intramuscularly (IM) by a healthcare professional.
Not for self-administration at home.
Known allergy to Ondansetron or similar medicines
Patients with congenital long QT syndrome
Severe liver disease (dose adjustment required)
Common: Headache, dizziness, constipation, injection site pain
Less common: Drowsiness, flushing, diarrhea
Rare but serious: Irregular heartbeat, allergic reaction, low blood pressure
Caution in patients with heart rhythm disorders or liver problems
May cause QT prolongation (heart rhythm changes)
Pregnant or breastfeeding women should use only under medical supervision
Inform doctor if taking any other antiemetic drugs
May interact with apomorphine (contraindicated)
Can interact with SSRIs, SNRIs (risk of serotonin syndrome)
Use caution with medicines affecting heart rhythm (e.g., amiodarone, quinidine)
Store below 30°C in a cool, dry place
Protect from light and moisture
Do not freeze
Keep away from children
Dispose of unused vials safely, per medical guidelines
Not a controlled substance
Prescription required
Usually given in hospitals before chemotherapy, radiotherapy, or surgery
May cause mild dizziness — avoid driving if affected
Stay hydrated during treatment to reduce side effects
Inform your doctor about any history of heart problems before starting
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